Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.54 |
| ▸ | ERN1 | O75460 | 1/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | APLNR | P35414 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.37 |
| ▸ | TUBB | P07437 | 2/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2093141 | 0.79 | ERN1 (0.49) | CYP1A2ERN1CYP1A1CYP1B1ALDH1A1 | |
| SCHEMBL10044958 | 0.78 | CYP1A2 (0.65) | CYP1A2CYP1A1CYP1B1MEN1KMT2A | |
| SCHEMBL2091596 | 0.78 | IDO1 (0.62) | ALDH1A1APLNRIDO1 | |
| SCHEMBL8203 | 0.78 | APLNR (0.59) | CYP1A2CYP1A1CYP1B1MEN1KMT2A | |
| SCHEMBL6995298 | 0.77 | CYP1A2 (0.54) | CYP1A2ERN1CYP1A1CYP1B1MEN1 | |
| SCHEMBL8395 | 0.75 | PTGS2 (0.53) | MEN1KMT2ATUBB1CYP3A4MAPT | |
| SCHEMBL900803 | 0.75 | CYP1A2 (0.61) | CYP1A2CYP1A1CYP1B1TUBB1APLNR | |
| SCHEMBL2093125 | 0.75 | ABCB1 (0.50) | CYP1A2MEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL7003958 | 0.73 | CYP3A4 (0.48) | MEN1KMT2AALDH1A1CYP3A4MAPT | |
| SCHEMBL27750315 | 0.73 | CYP1A2 (0.43) | CYP1A2ERN1MEN1KMT2ATUBB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1081149-B1 | PYRAZOLO 1,5-a]PYRIMIDINE DERIVATIVES | OTSUKA PHARMA CO LTD (JP) | 2003-04-02 | — | — | EP | disclosed |
| US-6372749-B1 | PHARMACOLOGICAL EFFECTS SUCH AS ANALGESIC ACTION, INHIBITORY EFFECT ON NITROGEN MONOXIDE SYNTHETASE AND THE LIKE AND ARE USEFUL AS ANALGESICS. | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2002-04-16 | — | — | US | disclosed |
| EP-1081149-A1 | PYRAZOLO 1,5-a]PYRIMIDINE DERIVATIVES | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2001-03-07 | — | — | EP | disclosed |