Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 8/20 | 0.62 |
| ▸ | KDM5A | P29375 | 2/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | CASP1 | P29466 | 2/20 | 0.46 |
| ▸ | CASP7 | P55210 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22445080 | 0.87 | MAOA (0.68) | MAOAKDM5AESR1ESR2KDM4E | |
| SCHEMBL28027195 | 0.81 | MAOA (0.58) | MAOAKDM5AESR1ESR2KDM4E | |
| SCHEMBL28748024 | 0.81 | MAOA (0.62) | MAOAKDM5AESR1ESR2KDM4E | |
| SCHEMBL5842359 | 0.79 | MAOA (0.60) | MAOAKDM5AESR1ESR2KDM4E | |
| SCHEMBL29124608 | 0.79 | MAOA (0.60) | MAOAKDM5AESR1ESR2KDM4E | |
| SCHEMBL29117642 | 0.79 | ELANE (0.46) | ESR1ESR2KDM4EALDH1A1RAB9A | |
| SCHEMBL29093498 | 0.78 | MAOA (0.59) | MAOAKDM5AESR1ESR2KDM4E | |
| SCHEMBL20346615 | 0.77 | MAOA (0.55) | MAOAKDM5AESR1ESR2KDM4E | |
| SCHEMBL640746 | 0.77 | MAOA (1.00) | MAOAKDM5AESR1ESR2KDM4E | |
| SCHEMBL3763290 | 0.77 | MAOA (0.71) | MAOAKDM5AESR1ESR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6048667-A | FREE RADICALS OR CATION POLYMERIZABLE OR PHOTOCROSSLINKABLE MONOMERS, SUBSTRATES AND PHOTOINITIATORS, BONDING WITH SUBSTRATES | CIBA SPECIALTY CHEMICALS CORP. (US) | 2000-04-11 | — | — | US | disclosed |