Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 11/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.57 |
| ▸ | CASP1 | P29466 | 1/20 | 0.57 |
| ▸ | CASP7 | P55210 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | KDM5A | P29375 | 2/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | MGAM | O43451 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | SI | P14410 | 1/20 | 0.51 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21874395 | 0.86 | MAOA (0.75) | MAOAKDM4EALDH1A1CYP3A4HPGD | |
| SCHEMBL29031922 | 0.83 | MAOA (0.67) | MAOAKDM4EALDH1A1CYP3A4HPGD | |
| SCHEMBL640746 | 0.83 | MAOA (1.00) | MAOAKDM4EALDH1A1CYP3A4HPGD | |
| SCHEMBL22445080 | 0.81 | MAOA (0.68) | MAOAKDM4EALDH1A1CYP3A4HPGD | |
| SCHEMBL3837760 | 0.80 | MAOA (0.67) | MAOAKDM4EALDH1A1CYP3A4HPGD | |
| SCHEMBL6893811 | 0.79 | MAOA (0.69) | MAOAKDM4EALDH1A1CYP3A4HPGD | |
| SCHEMBL6859087 | 0.79 | MAOA (0.60) | MAOAKDM4EALDH1A1CYP3A4HPGD | |
| SCHEMBL5842359 | 0.79 | MAOA (0.60) | MAOAKDM4EALDH1A1CYP3A4HPGD | |
| SCHEMBL27612080 | 0.78 | MAOA (0.63) | MAOAKDM4EALDH1A1CYP3A4HPGD | |
| SCHEMBL8203513 | 0.77 | MAOA (0.62) | MAOAKDM4EALDH1A1CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955062-A | LOTION SUCH AS A SUNSCREEN INCLUDES A PH INDICATOR WHICH COLORIZES THE LOTION UNTIL THE LOTION IS APPLIED TO THE HUMAN SKIN, WHEREINAFTER THE COLORED LOTION TURNS CLEAR | SEEUV (US) | 1999-09-21 | — | — | US | claimed |
| US-5753210-A | SUNSCREEN PROTECTIVE COLLOID COMPRISING A PH INDICATOR BECOME DISCOLORING WHEN CONTACT WITH THE SKIN; COSMETICS | SEEUV (US) | 1998-05-19 | — | — | US | claimed |
| US-5567420-A | SUCH AS SUNSCREEN AGENT | GE CANADA FINANCE HOLDING COMPANY (CA) | 1996-10-22 | — | — | US | claimed |
| WO-1996014826-A1 | LOTION WHICH IS TEMPORARILY COLORED UPON APPLICATION | SEEUV (US) | 1996-05-23 | — | — | WO | claimed |
| US-8263644-B2 | Cytotoxic xanthone compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-09-11 | — | — | US | disclosed |
| US-20100311826-A1 | CYTOTOXIC XANTHONE COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY | 2010-12-09 | — | — | US | disclosed |
| WO-2009036106-A1 | CYTOTOXIC XANTHONE COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-03-19 | — | — | WO | disclosed |
| US-6086858-A | SUNSCREEN COMPOSITION WITH A BRIGHT COLOR INDICATOR WHICH CONTRASTS HUMAN SKIN TO DISCERN AN AREA COVERED BY THE COMPOSITION AND ENSURING EVEN COVERAGE, THEN DISAPPEARS AFTER DISTRIBUTION ON THE SKIN | IPA, LLC (US) | 2000-07-11 | — | — | US | disclosed |
| US-5958383-A | SUNSCREEN CONTAINING A COLORANT OF COLOR OTHER THAN HUMAN SKIN, CAPABLE OF DISAPPEARING WHEN DISTRIBUTED OVER SKIN; ENSURES UNIFORM APPLICATION BEFORE COLOR DISAPPEARS | IPA, L.L.C. (US) | 1999-09-28 | — | — | US | disclosed |
| US-5955062-A | LOTION SUCH AS A SUNSCREEN INCLUDES A PH INDICATOR WHICH COLORIZES THE LOTION UNTIL THE LOTION IS APPLIED TO THE HUMAN SKIN, WHEREINAFTER THE COLORED LOTION TURNS CLEAR | SEEUV (US) | 1999-09-21 | — | — | US | disclosed |
| US-5753210-A | SUNSCREEN PROTECTIVE COLLOID COMPRISING A PH INDICATOR BECOME DISCOLORING WHEN CONTACT WITH THE SKIN; COSMETICS | SEEUV (US) | 1998-05-19 | — | — | US | disclosed |
| US-5680962-A | Lotion which is temporarily colored upon application | IPA, LLC, A TEXAS LIMITED LIABILITY COMPANY | 1997-10-28 | — | — | US | disclosed |
| US-5567420-A | SUCH AS SUNSCREEN AGENT | GE CANADA FINANCE HOLDING COMPANY (CA) | 1996-10-22 | — | — | US | disclosed |
| WO-1996014826-A1 | LOTION WHICH IS TEMPORARILY COLORED UPON APPLICATION | SEEUV (US) | 1996-05-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100311826-A1 | CYTOTOXIC XANTHONE COMPOUNDS | XPA, XPO5, ANXA5 | MAOA 3023/4885KDM4E 3945/4885ALDH1A1 4426/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.