Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 3/20 | 0.47 |
| ▸ | CTSK | P43235 | 2/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KLK7 | P49862 | 1/20 | 0.43 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8220722 | 0.84 | HTR2C (0.53) | PREPHTR2CCTRB1TSHRNPSR1 | |
| SCHEMBL7251746 | 0.84 | HTR2C (0.53) | PREPHTR2CCTRB1TSHRNPSR1 | |
| SCHEMBL4674934 | 0.83 | HTR2C (0.52) | PREPHTR2CCTRB1NPSR1NPC1 | |
| SCHEMBL375940 | 0.83 | KLK7 (0.50) | PREPCTSKCTSBCTSSHTR2C | |
| SCHEMBL12479521 | 0.82 | SMN1; SMN2 (0.53) | PREPHTR2CCTRB1TSHRNPSR1 | |
| SCHEMBL7909480 | 0.81 | HTR2C (0.50) | PREPHTR2CCTRB1TSHRNPSR1 | |
| Hydrochloric Acid SCHEMBL1532877 | 0.81 | SMN1; SMN2 (0.52) | PREPHTR2CCTRB1TSHRNPSR1 | |
| SCHEMBL28978066 | 0.81 | HTR2C (0.50) | PREPHTR2CCTRB1TSHRNPSR1 | |
| SCHEMBL6501753 | 0.80 | HTR2C (0.52) | PREPCTSKHTR2CCTRB1TSHR | |
| SCHEMBL6487292 | 0.80 | HTR2C (0.52) | PREPCTSKHTR2CCTRB1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2295410-A1 | HDAC inhibitor | Chroma Therapeutics Limited (GB) | 2011-03-16 | — | — | EP | disclosed |
| WO-2008040934-A1 | HDAC INHIBITORS | CHROMA THERAPEUTICS LTD. (GB) | 2008-04-10 | — | — | WO | disclosed |