Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | KDM1B | Q8NB78 | 2/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.36 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8200061 | 0.86 | ALDH1A1 (0.33) | CYP1A1CYP1A2CYP2E1CYP3A4CYP2C8 | |
| SCHEMBL196765 | 0.66 | CYP3A4 (0.73) | DYRK1ACLK4NISCHCYP1A1CYP1A2 | |
| SCHEMBL29489425 | 0.66 | CYP3A4 (0.73) | DYRK1ACLK4NISCHCYP1A1CYP1A2 | |
| SCHEMBL8201027 | 0.66 | DYRK1A (0.39) | AKR1C3AKR1C2DYRK1ACLK4NISCH | |
| SCHEMBL5887546 | 0.65 | DYRK1A (0.44) | DYRK1ACLK4NISCHCYP1A1CYP1A2 | |
| SCHEMBL487170 | 0.65 | CYP1A1 (0.53) | AKR1C3AKR1C2DYRK1ACLK4CYP1A1 | |
| Hydrogen Sulfide SCHEMBL28640169 | 0.64 | CYP3A4 (0.70) | DYRK1ACLK4NISCHCYP1A1CYP1A2 | |
| Ammonia Solution, Strong SCHEMBL27960505 | 0.64 | CYP3A4 (0.70) | DYRK1ACLK4NISCHCYP1A1CYP1A2 | |
| SCHEMBL29628977 | 0.64 | CYP3A4 (0.77) | DYRK1ACLK4NISCHCYP1A1CYP1A2 | |
| SCHEMBL6047660 | 0.64 | ALDH1A1 (0.40) | DYRK1ACLK4NISCHCYP1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6140344-A | FOR TREATING PATHOLOGICAL CONDITIONS SUCH AS ASTHMA, RHINITIS, ECZEMA AND PARASITIC INFECTIONS FEATURING TISSUE EOSINOPHILIA | SYNTEX (U.S.A.) INC. (US) | 2000-10-31 | — | — | US | disclosed |