SCHEMBL820375

SCHEMBL820375

O=C(O)CC(Cl)CC(F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SLC22A6 Q4U2R8 1/20 0.36
TDP1 Q9NUW8 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.33
GABRR1 P24046 2/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11299621 0.82 SLC22A6 (0.33) SLC22A6TDP1SMN1; SMN2
Hydrochloric Acid SCHEMBL11295122 0.80 SLC22A6 (0.32) SLC22A6TDP1SMN1; SMN2
SCHEMBL11295903 0.80 SLC22A6 (0.32) SLC22A6TDP1SMN1; SMN2
Hydrochloric Acid SCHEMBL11296962 0.79 SLC22A6 (0.31) SLC22A6TDP1
Hydrochloric Acid SCHEMBL11490820 0.76 SMN1; SMN2 (0.39) SLC22A6TDP1SMN1; SMN2GABRR1LMNA
SCHEMBL6467551 0.76 SLC22A6 (0.36) SLC22A6TDP1SMN1; SMN2GABRR1LMNA
SCHEMBL1262446 0.76 SLC22A6 (0.50) SLC22A6TDP1SMN1; SMN2GABRR1LMNA
SCHEMBL6734706 0.73 SLC22A6 (0.47) SLC22A6TDP1SMN1; SMN2GABRR1LMNA
SCHEMBL2037940 0.73 SLC22A6 (0.38) SLC22A6TDP1SMN1; SMN2GABRR1LMNA
SCHEMBL8018447 0.73 ALDH1A1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1930310-B1 PROCESS FOR PRODUCING 3,3,3-TRIFLUOROPROPIONALDEHYDE CENTRAL GLASS CO LTD (JP) 2011-11-16 EP disclosed
US-20110263941-A1 ENDOSCOPE DESIGNS AND METHODS OF MANUFACTURE Intergrated Endoscopy,Inc. (US) 2011-10-27 US disclosed
US-7544844-B2 Process for producing 3,3,3-trifluoropropionaldehyde CENTRAL GLASS COMPANY, LIMITED (JP) 2009-06-09 US disclosed
US-20090105506-A1 Process for Producing 3,3,3-Trifluoropropionaldehyde CENTRAL GLASS COMPANY, LIMITED (JP) 2009-04-23 US disclosed
EP-1930310-A1 PROCESS FOR PRODUCING 3,3,3-TRIFLUOROPROPIONALDEHYDE Central Glass Co., Ltd. (JP) 2008-06-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090105506-A1 Process for Producing 3,3,3-Trifluoropropionaldehyde ALDH1A3, ALDH7A1, ALDH1A1 SLC22A6 4285/4885TDP1 2889/4885SMN1; SMN2 3248/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.