Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 16/20 | 0.74 |
| ▸ | AVPR1A | P37288 | 11/20 | 0.74 |
| ▸ | AVPR1B | P47901 | 4/20 | 0.60 |
| ▸ | OXTR | P30559 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6993733 | 0.99 | AVPR2 (0.73) | AVPR2AVPR1AAVPR1BOXTR | |
| SCHEMBL10109005 | 0.90 | AVPR2 (0.70) | AVPR2AVPR1AAVPR1BOXTR | |
| SCHEMBL17471541 | 0.87 | AVPR2 (0.68) | AVPR2AVPR1AAVPR1BOXTR | |
| Conivaptan SCHEMBL49815 | 0.85 | AVPR2 (1.00) | AVPR2AVPR1AAVPR1BOXTR | |
| SCHEMBL6991859 | 0.85 | AVPR1A (0.72) | AVPR2AVPR1AAVPR1BOXTR | |
| Conivaptan SCHEMBL28043077 | 0.84 | AVPR2 (0.98) | AVPR2AVPR1AAVPR1BOXTR | |
| Conivaptan SCHEMBL1649913 | 0.83 | AVPR2 (0.97) | AVPR2AVPR1AAVPR1BOXTR | |
| SCHEMBL6619403 | 0.81 | AVPR2 (0.65) | AVPR2AVPR1AAVPR1BOXTR | |
| SCHEMBL6995135 | 0.80 | AVPR2 (0.48) | AVPR2AVPR1AOXTR | |
| Conivaptan SCHEMBL4625101 | 0.80 | AVPR2 (0.75) | AVPR2AVPR1AAVPR1BOXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008097546-A2 | COMPOUNDS THAT INHIBIT CHOLINESTERASE | COLUCID PHARMACEUTICALS, INC. (US) | 2008-08-14 | — | — | WO | disclosed |