Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 16/20 | 0.65 |
| ▸ | AVPR1A | P37288 | 14/20 | 0.65 |
| ▸ | OXTR | P30559 | 1/20 | 0.59 |
| ▸ | AVPR1B | P47901 | 4/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6993535 | 0.95 | AVPR2 (0.59) | AVPR2AVPR1AOXTRAVPR1B | |
| SCHEMBL1495876 | 0.84 | ALDH1A1 (0.49) | AVPR2AVPR1A | |
| Conivaptan SCHEMBL4625101 | 0.82 | AVPR2 (0.75) | AVPR2AVPR1AOXTRAVPR1B | |
| Conivaptan SCHEMBL29406590 | 0.82 | AVPR2 (0.75) | AVPR2AVPR1AOXTRAVPR1B | |
| SCHEMBL17471541 | 0.82 | AVPR2 (0.68) | AVPR2AVPR1AOXTRAVPR1B | |
| Conivaptan SCHEMBL387232 | 0.82 | AVPR2 (0.74) | AVPR2AVPR1AOXTRAVPR1B | |
| SCHEMBL8204092 | 0.81 | AVPR2 (0.74) | AVPR2AVPR1AOXTRAVPR1B | |
| Hydrochloric Acid SCHEMBL6993733 | 0.81 | AVPR2 (0.73) | AVPR2AVPR1AOXTRAVPR1B | |
| SCHEMBL6991859 | 0.80 | AVPR1A (0.72) | AVPR2AVPR1AOXTRAVPR1B | |
| SCHEMBL10281263 | 0.80 | AVPR2 (0.65) | AVPR2AVPR1AOXTRAVPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097920-B1 | Intermediate for condensed benzazepine derivatives | YAMANOUCHI PHARMA CO LTD (JP) | 2004-09-22 | — | — | EP | disclosed |
| EP-0709386-B1 | FUSED BENZAZEPINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | YAMANOUCHI PHARMA CO LTD (JP) | 2003-05-07 | — | — | EP | disclosed |
| EP-1097920-A1 | Intermediate for condensed benzazepine derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2001-05-09 | — | — | EP | disclosed |
| EP-0709386-A1 | FUSED BENZAZEPINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-05-01 | — | — | EP | disclosed |