Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 10/20 | 0.85 |
| ▸ | SLCO1B1 | Q9Y6L6 | 4/20 | 0.85 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.85 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.85 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.85 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.85 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.85 |
| ▸ | RHOC | P08134 | 1/20 | 0.85 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.85 |
| ▸ | THRB | P10828 | 1/20 | 0.85 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.85 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.85 |
| ▸ | ABCC3 | O15438 | 2/20 | 0.74 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.74 |
| ▸ | SLCO1B3 | Q9NPD5 | 2/20 | 0.74 |
| ▸ | PDE6D | O43924 | 3/20 | 0.66 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4428595 | 0.95 | HMGCR (0.90) | HMGCRSLCO1B1ABCB11HDAC1HDAC2 | |
| SCHEMBL4787702 | 0.95 | HMGCR (0.90) | HMGCRSLCO1B1ABCB11HDAC1HDAC2 | |
| SCHEMBL27952561 | 0.94 | HMGCR (0.88) | HMGCRSLCO1B1ABCB11HDAC1HDAC2 | |
| SCHEMBL28890295 | 0.94 | HMGCR (0.84) | HMGCRSLCO1B1ABCB11HDAC1HDAC2 | |
| SCHEMBL28890294 | 0.94 | HMGCR (0.84) | HMGCRSLCO1B1ABCB11HDAC1HDAC2 | |
| SCHEMBL28890967 | 0.93 | HMGCR (0.82) | HMGCRSLCO1B1ABCB11HDAC1HDAC2 | |
| SCHEMBL28890969 | 0.93 | HMGCR (0.82) | HMGCRSLCO1B1ABCB11HDAC1HDAC2 | |
| SCHEMBL4428234 | 0.93 | HMGCR (0.85) | HMGCRSLCO1B1ABCB11HDAC1HDAC2 | |
| SCHEMBL15492882 | 0.93 | HMGCR (0.85) | HMGCRSLCO1B1ABCB11HDAC1HDAC2 | |
| SCHEMBL10108890 | 0.93 | HMGCR (0.85) | HMGCRSLCO1B1ABCB11HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140058106-A1 | SYSTEM FOR FLUORINATING ORGANIC COMPOUNDS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2014-02-27 | — | — | US | disclosed |
| US-20110054175-A1 | SYSTEM FOR FLUORINATING ORGANIC COMPOUNDS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2011-03-03 | — | — | US | disclosed |
| US-20110054175-A1 | SYSTEM FOR FLUORINATING ORGANIC COMPOUNDS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2011-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140058106-A1 | SYSTEM FOR FLUORINATING ORGANIC COMPOUNDS | PFAS, ODC1, AOC1 | HMGCR 2883/4885SLCO1B1 47/4885ABCB11 2017/4885 |
| US-20110054175-A1 | SYSTEM FOR FLUORINATING ORGANIC COMPOUNDS | PFAS, ODC1, AOC1 | HMGCR 2883/4885SLCO1B1 47/4885ABCB11 2017/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.