Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | HTR2C | P28335 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL166764 | 0.77 | CHRM5 (0.46) | ALDH1A1MEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL6179170 | 0.77 | CHRM5 (0.46) | ALDH1A1MEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL20292058 | 0.77 | CHRM5 (0.46) | ALDH1A1MEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL5802520 | 0.76 | ALDH1A1 (0.37) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL9786152 | 0.76 | ALDH1A1 (0.37) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL7008410 | 0.76 | MEN1 (0.46) | ALDH1A1MEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL4599754 | 0.74 | MEN1 (0.45) | ALDH1A1MEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL4974328 | 0.71 | NOS2 (0.35) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL4974333 | 0.71 | NOS2 (0.35) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL22589075 | 0.71 | ALDH1A1 (0.38) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6110939-A | AS A SUBSTANCE P ANTAGONISTS TREATING TACHYKININ-MEDIATED DISEASE, ASTHMA, CENTRAL NERVOUS SYSTEM DISORDER | JANSSEN PHARMACEUTICA N.V. (BE) | 2000-08-29 | — | — | US | disclosed |