Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2352112 | 0.84 | CYP19A1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL2353267 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL650445 | 0.76 | POLB (0.31) | — | |
| Hydrochloric Acid SCHEMBL820006 | 0.75 | CYP19A1 (0.33) | — | |
| Hydrochloric Acid SCHEMBL2860378 | 0.74 | CYP1A2 (0.30) | — | |
| Hydrochloric Acid SCHEMBL1236219 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL2859895 | 0.73 | ALDH1A1 (0.33) | — | |
| Hydrochloric Acid SCHEMBL5702774 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL6554727 | 0.70 | POLB (0.31) | — | |
| Hydrochloric Acid SCHEMBL4238189 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2591011-B1 | MULTI-COMPONENT CATALYST SYSTEMS AND POLYMERIZATION PROCESSES FOR FORMING BROAD COMPOSITION DISTRIBUTION POLYMERS | FINA TECHNOLOGY (US) | 2016-04-06 | — | — | EP | claimed |
| US-8445595-B2 | Polypropylene prepared with a single-site catalyst and poly(hydroxyl carboxylic acid) blends | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2013-05-21 | — | — | US | claimed |
| EP-2591011-A1 | MULTI-COMPONENT CATALYST SYSTEMS AND POLYMERIZATION PROCESSES FOR FORMING BROAD COMPOSITION DISTRIBUTION POLYMERS | Fina Technology, Inc. (US) | 2013-05-15 | — | — | EP | claimed |
| EP-2160233-B1 | PROCESS FOR THE POLYMERISATION OF OLEFINS | TOTAL RES & TECHNOLOGY FELUY (BE) | 2012-10-17 | — | — | EP | claimed |
| US-8278403-B2 | Multi-component catalyst systems and polymerization processes for forming broad composition distribution polymers | FINA TECHNOLOGY, INC. (US) | 2012-10-02 | — | — | US | claimed |
| WO-2012005937-A1 | MULTI-COMPONENT CATALYST SYSTEMS AND POLYMERIZATION PROCESSES FOR FORMING BROAD COMPOSITION DISTRIBUTION POLYMERS | FINA TECHNOLOGY, INC. (US) | 2012-01-12 | — | — | WO | claimed |
| US-20120010376-A1 | Multi-Component Catalyst Systems and Polymerization Processes for Forming Broad Composition Distribution Polymers | FINA TECHNOLOGY, INC. (US) | 2012-01-12 | — | — | US | claimed |
| US-8003739-B2 | Multi-component catalyst systems and polymerization processes for forming in-situ heterophasic copolymers and/or varying the xylene solubles content of polyolefins | FINA TECHNOLOGY, INC. (US) | 2011-08-23 | — | — | US | claimed |
| US-20100234544-A1 | Process for the Polymerisation of Olefins | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2010-09-16 | — | — | US | claimed |
| EP-2160233-A1 | PROCESS FOR THE POLYMERISATION OF OLEFINS | Total Petrochemicals Research Feluy (BE) | 2010-03-10 | — | — | EP | claimed |
| WO-2009000782-A1 | PROCESS FOR THE POLYMERISATION OF OLEFINS | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2008-12-31 | — | — | WO | claimed |
| EP-2006012-A1 | Process for the polymerisation of olefins | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2008-12-24 | — | — | EP | claimed |
| EP-2591011-B1 | MULTI-COMPONENT CATALYST SYSTEMS AND POLYMERIZATION PROCESSES FOR FORMING BROAD COMPOSITION DISTRIBUTION POLYMERS | FINA TECHNOLOGY (US) | 2016-04-06 | — | — | EP | disclosed |
| WO-2014006069-A1 | PROCESS FOR THE POLYMERIZATION OF OLEFINS | TOTAL RESEARCH & TECHNOLOGY FELUY (BE) | 2014-01-09 | — | — | WO | disclosed |
| US-20130225707-A1 | Articles Formed From Polypropylene Prepared with a Single-Site Catalyst and Poly(hydroxyl carboxylic acid) Blends | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2013-08-29 | — | — | US | disclosed |
| US-8461276-B2 | Multi-component catalyst systems and polymerization processes for forming broad composition distribution polymers | FINA TECHNOLOGY, INC. (US) | 2013-06-11 | — | — | US | disclosed |
| US-20100047571-A1 | Process of Making Bicomponent Fiber | FINA TECHNOLOGY, INC. (US) | 2010-02-25 | — | — | US | disclosed |
| WO-2009027378-A1 | POLYPROPYLENE PREPARED WITH A SINGLE-SITE CATALYST AND POLY(HYDROXY CARBOXYLIC ACID) BLENDS | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2009-03-05 | — | — | WO | disclosed |
| WO-2009000782-A1 | PROCESS FOR THE POLYMERISATION OF OLEFINS | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2008-12-31 | — | — | WO | disclosed |
| EP-2006012-A1 | Process for the polymerisation of olefins | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2008-12-24 | — | — | EP | disclosed |