Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5681862 | 0.87 | MEN1 (0.32) | TSHR | |
| SCHEMBL10444 | 0.83 | — | — | |
| SCHEMBL10794688 | 0.83 | TSHR (0.46) | TSHRTDP1 | |
| Hydrochloric Acid SCHEMBL7715252 | 0.80 | — | — | |
| SCHEMBL20076234 | 0.77 | TSHR (0.30) | TSHRTDP1 | |
| SCHEMBL10954286 | 0.77 | TSHR (0.30) | TSHRTDP1 | |
| SCHEMBL14564963 | 0.75 | TSHR (0.33) | TSHRTDP1 | |
| SCHEMBL13896428 | 0.75 | MEN1 (0.32) | TSHR | |
| SCHEMBL5366938 | 0.75 | TSHR (0.33) | TSHRTDP1 | |
| SCHEMBL2625536 | 0.73 | MEN1 (0.30) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101613427-B | Method for preparing polyisobutylene with high reaction activity | UNIV BEIJING CHEMICAL | 2011-04-20 | — | — | CN | claimed |
| CN-101613427-A | The preparation method of high-activity polyisobutylene | UNIV BEIJING CHEMICAL | 2009-12-30 | — | — | CN | claimed |
| US-20150105445-A1 | RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING CHEMICALLY MODIFIED SHORT INTERFERING NUCLEIC ACID (siNA) | SIRNA THERAPEUTICS, INC. (US) | 2015-04-16 | — | — | US | disclosed |
| CN-101955558-B | Initiating system for preparing high-reaction activity polyisobutene and copolymer of polyisobutene | UNIV BEIJING CHEMICAL | 2013-03-13 | — | — | CN | disclosed |
| CN-101613427-B | Method for preparing polyisobutylene with high reaction activity | UNIV BEIJING CHEMICAL | 2011-04-20 | — | — | CN | disclosed |
| US-7906207-B2 | Coating composition, optical film, anti-reflection film, polarizing plate, and display unit using them | FUJIFILM CORPORATION (JP) | 2011-03-15 | — | — | US | disclosed |
| CN-101955558-A | Initiating system for preparing high-reaction activity polyisobutene and copolymer of polyisobutene | UNIV BEIJING CHEMICAL | 2011-01-26 | — | — | CN | disclosed |
| US-20100317048-A1 | NOVEL SYNTHETIC BLOCKING REAGENTS | FORSCHUNGSZENTRUM BORSTEL (DE) | 2010-12-16 | — | — | US | disclosed |
| CN-101613427-A | The preparation method of high-activity polyisobutylene | UNIV BEIJING CHEMICAL | 2009-12-30 | — | — | CN | disclosed |
| WO-2008033747-A9 | MULTI-FUNCTIONAL SMALL MOLECULES AS ANTI-PROLIFERATIVE AGENTS | CURIS INC (MA) | 2008-07-24 | — | — | WO | disclosed |
| US-20080167313-A1 | 1,2,4-Triazine Derivatives, Preparation and Use Thereof in Human Therapy | PIERRE FABRE MEDICAMENT (FR) | 2008-07-10 | — | — | US | disclosed |
| WO-2008033744-A2 | DNA METHYL TRANSFERASE INHIBITORS CONTAINING A ZINC BINDING MOIETY | CURIS, INC. (US) | 2008-03-20 | — | — | WO | disclosed |
| WO-2008033747-A2 | MULTI-FUNCTIONAL SMALL MOLECULES AS ANTI-PROLIFERATIVE AGENTS | CURIS, INC. (US) | 2008-03-20 | — | — | WO | disclosed |
| US-20070289497-A1 | Coating Composition, Optical Film, Anti-reflection Film, Polarizing Plate, and Display Unit Using Them | FUJIFILM CORPORATION (JP) | 2007-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317048-A1 | NOVEL SYNTHETIC BLOCKING REAGENTS | SPR, SSB, LY96 | TSHR 1408/4885TDP1 3668/4885 |
| US-20080167313-A1 | 1,2,4-Triazine Derivatives, Preparation and Use Thereof in Human Therapy | CBR3, NOX3, RTN3 | TSHR 133/4885TDP1 2250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.