Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 6/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 6/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.33 |
| ▸ | F10 | P00742 | 4/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
| ▸ | ITGAV | P06756 | 1/20 | 0.33 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 4/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.31 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.30 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.30 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.30 |
| ▸ | PLG | P00747 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8202071 | 0.93 | HDAC6 (0.38) | OPRM1OPRD1OPRK1ITGB3PRSS1 | |
| SCHEMBL8207131 | 0.91 | ITGB3 (0.32) | ITGB3PRSS1PRSS2PRSS3ITGA2B | |
| SCHEMBL8205561 | 0.91 | ITGB3 (0.37) | OPRM1OPRD1OPRK1ITGB3PRSS1 | |
| SCHEMBL8202871 | 0.86 | HDAC6 (0.43) | OPRM1OPRD1OPRK1ITGB3PRSS1 | |
| SCHEMBL13007352 | 0.84 | HDAC3 (0.38) | ITGB3PRSS1PRSS2PRSS3ITGA2B | |
| SCHEMBL8202087 | 0.84 | HDAC6 (0.39) | ITGB3HDAC6ITGB1ITGAVITGA5 | |
| SCHEMBL8206345 | 0.84 | HDAC6 (0.40) | OPRM1OPRD1OPRK1ITGB3PRSS1 | |
| SCHEMBL13007366 | 0.84 | HDAC3 (0.36) | ITGB3PRSS1PRSS2PRSS3ITGA2B | |
| SCHEMBL8203124 | 0.82 | HDAC3 (0.34) | F10HDAC6HDAC3HDAC8 | |
| SCHEMBL8203576 | 0.81 | HDAC6 (0.54) | OPRM1OPRD1OPRK1ITGB3PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008053131-A1 | HYDROXAMATES AS INHIBITORS OF HISTONE DEACETYLASE | CHROMA THERAPEUTICS LTD. (GB) | 2008-05-08 | — | — | WO | disclosed |