Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 6/20 | 0.46 |
| ▸ | GNAO1 | P09471 | 6/20 | 0.46 |
| ▸ | GNAI1 | P63096 | 6/20 | 0.46 |
| ▸ | GUSB | P08236 | 2/20 | 0.38 |
| ▸ | EBP | Q15125 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL651943 | 0.86 | GNAO1 (0.52) | GNAI3GNAO1GNAI1GUSBEBP | |
| SCHEMBL9432137 | 0.84 | GNAO1 (0.55) | GNAI3GNAO1GNAI1GUSBEBP | |
| SCHEMBL10776413 | 0.84 | GNAO1 (0.55) | GNAI3GNAO1GNAI1GUSBEBP | |
| SCHEMBL10773791 | 0.84 | GNAO1 (0.55) | GNAI3GNAO1GNAI1GUSBEBP | |
| SCHEMBL10593959 | 0.84 | GNAO1 (0.55) | GNAI3GNAO1GNAI1GUSBEBP | |
| SCHEMBL4681475 | 0.84 | GNAO1 (0.55) | GNAI3GNAO1GNAI1GUSBEBP | |
| SCHEMBL9433020 | 0.84 | GNAO1 (0.55) | GNAI3GNAO1GNAI1GUSBEBP | |
| SCHEMBL9357117 | 0.81 | GNAI3 (0.36) | GNAI3GNAO1GNAI1BCHECYP1A2 | |
| SCHEMBL42184 | 0.79 | GNAI3 (0.43) | GNAI3GNAO1GNAI1SIGMAR1S1PR1 | |
| SCHEMBL447333 | 0.79 | GNAI3 (0.46) | GNAI3GNAO1GNAI1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000032586-A1 | METHOD FOR PREPARING 3-CHROMENE DERIVATIVES, USE OF SAID DERIVATIVES FOR PREPARING THIAZOLIDINONES | RHODIA CHIMIE (FR) | 2000-06-08 | — | — | WO | disclosed |
| WO-1999006392-A1 | METHOD FOR PREPARING 2H-1 BENZOPYRANES AND SYNTHESIS INTERMEDIATES | RHODIA CHIMIE (FR) | 1999-02-11 | — | — | WO | disclosed |
| EP-0277836-B1 | THIAZOLIDINONE DERIVATIVES, THEIR PREPARATION AND THEIR USE | Sankyo Company Limited (JP) | 1993-06-02 | — | — | EP | disclosed |
| US-4873255-A | REDUCE BLOOD GLUCOSE AND BLOOD LIPID LEVELS | SANKYO COMPANY LIMITED (JP) | 1989-10-10 | — | — | US | disclosed |
| EP-0277836-A1 | Thiazolidinone derivatives, their preparation and their use | Sankyo Company Limited (JP) | 1988-08-10 | — | — | EP | disclosed |