SCHEMBL8204734

SCHEMBL8204734

CC1(c2ccc(Cl)cc2)NC1(C)c1ccc(Cl)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.42
CYP2A6 P11509 1/20 0.42
MAPK1 P28482 1/20 0.41
KMT2A Q03164 1/20 0.41
DRD2 P14416 1/20 0.39
SLC6A4 P31645 6/20 0.38
SLC6A3 Q01959 6/20 0.38
SLC6A2 P23975 3/20 0.38
CHRNA1 P02708 1/20 0.38
CHRNG P07510 1/20 0.38
CHRNB1 P11230 1/20 0.38
CHRNB2 P17787 1/20 0.38
CHRNB4 P30926 1/20 0.38
CHRNA3 P32297 1/20 0.38
CHRNA4 P43681 1/20 0.38
CHRND Q07001 1/20 0.38
HTR6 P50406 1/20 0.37
MAOA P21397 2/20 0.37
MAOB P27338 2/20 0.37
KDM1A O60341 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8210195 0.74 TSHR (0.42) SLC6A4SLC6A3SLC6A2CHRNA1CHRNG
SCHEMBL8202769 0.73 SLC6A4 (0.42) SLC6A4SLC6A3SLC6A2CHRNA1CHRNG
SCHEMBL8195018 0.72 SLC6A3 (0.44) SLC6A4SLC6A3SLC6A2CHRNA1CHRNG
SCHEMBL10046441 0.70 SLC6A4 (0.43) LMNACYP2A6MAPK1KMT2ADRD2
SCHEMBL8202752 0.69 SLC6A4 (0.38) LMNACYP2A6MAPK1KMT2ADRD2
SCHEMBL435094 0.68 SLC6A4 (0.44) LMNACYP2A6MAPK1KMT2ADRD2
SCHEMBL8207892 0.67 TP53 (0.42)
SCHEMBL8204831 0.67 TSHR (0.43) LMNAMAPK1KMT2ASLC6A4SLC6A3
SCHEMBL655680 0.66 DRD2 (0.60) MAPK1KMT2ADRD2SLC6A4SLC6A3
SCHEMBL8204306 0.66 SLC6A4 (0.36) LMNACYP2A6MAPK1KMT2ADRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6093851-A N-(α-alkylbenzylidene)-α-phenylalkylamine, its use and process for producing the same and process for producing intermediate therefor SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2000-07-25 US disclosed
EP-0735018-B1 N-(alpha-alkylbenzylidene)-alpha-phenylalkylamine, its use and process for producing the same and process for producing intermediate therefor SUMITOMO CHEMICAL CO (JP) 1999-07-21 EP disclosed
US-5739401-A N-(α-alkylbenzylidene)-α-phenylalkylamine, its use and process for producing the same and process for producing intermediate therefor SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-04-14 US disclosed
EP-0735018-A1 N-(alpha-alkylbenzylidene)-alpha-phenylalkylamine, its use and process for producing the same and process for producing intermediate therefor SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1996-10-02 EP disclosed