Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | RXRG | P48443 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 6/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5511230 | 0.83 | NPC1 (0.51) | RXRARXRBRXRGPPARDPPARA | |
| SCHEMBL5514300 | 0.83 | PPARD (0.46) | RXRARXRBRXRGPPARDPPARA | |
| SCHEMBL6674358 | 0.80 | SMPD1 (0.56) | APP | |
| SCHEMBL30889094 | 0.80 | APP (0.63) | RXRAMAOBIDO1APP | |
| SCHEMBL1332171 | 0.79 | HTR2C (0.59) | RXRARXRBRXRGSLC6A4 | |
| SCHEMBL30354895 | 0.77 | MAOB (0.57) | MAOBSLC6A4IDO1 | |
| SCHEMBL16797024 | 0.75 | KDM4E (0.60) | MAOB | |
| SCHEMBL855955 | 0.75 | MAOB (0.62) | RXRARXRBRXRGMAOB | |
| SCHEMBL5052312 | 0.74 | NPC1 (0.57) | APP | |
| SCHEMBL856842 | 0.74 | ALDH1A1 (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6043226-A | TREATING BACTERIAL, PARASITIC AND PROTOZOAL INFECTIONS | PFIZER INC. (US) | 2000-03-28 | — | — | US | disclosed |