SCHEMBL820510

SCHEMBL820510

O=C1NCCc2ccccc2CCN1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP11 Q9NR21 4/20 0.59
PARP10 Q53GL7 3/20 0.59
PDPK1 O15530 1/20 0.59
PARP1 P09874 1/20 0.59
HTR2C P28335 1/20 0.56
PNMT P11086 1/20 0.50
CD44 P16070 1/20 0.50
MAOB P27338 1/20 0.50
CYP2A6 P11509 1/20 0.44
TSHR P16473 1/20 0.43
CRBN Q96SW2 2/20 0.42
TUBB4A P04350 1/20 0.42
TUBB P07437 1/20 0.42
TUBA3C P0DPH7 1/20 0.42
TUBA1B P68363 1/20 0.42
TUBA4A P68366 1/20 0.42
TUBB4B P68371 1/20 0.42
TUBB3 Q13509 1/20 0.42
TUBB2A Q13885 1/20 0.42
TUBB8 Q3ZCM7 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11877329 0.86 TSHR (0.52) PARP11PARP10PDPK1PARP1HTR2C
SCHEMBL29119467 0.81 PARP10 (0.55) PARP11PARP10PDPK1PARP1HTR2C
SCHEMBL1196991 0.81 NPC1 (0.57) PARP11PARP10PDPK1PARP1HTR2C
SCHEMBL2061125 0.79 PARP10 (0.53) PARP11PARP10PDPK1PARP1HTR2C
SCHEMBL29369705 0.75 PARP10 (1.00) PARP11PARP10PDPK1PARP1TUBB4A
SCHEMBL67710 0.75 PARP10 (1.00) PARP11PARP10PDPK1PARP1TUBB4A
SCHEMBL14061414 0.74 CA12 (0.56) PARP11PARP10PDPK1PARP1PNMT
SCHEMBL7262152 0.74 CRBN (0.46) PARP11PARP10PDPK1PARP1CRBN
Hydrochloric Acid SCHEMBL10647408 0.73 PARP10 (0.96) PARP11PARP10PDPK1PARP1TUBB4A
SCHEMBL175146 0.73 HTR2C (1.00) PARP11PARP10PDPK1PARP1HTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4403049-A POLYMERIZING A SPINNING OIL OF EPOXY COMPOUND, AN ETHYLENE UREA UNITIKA LIMITED (JP) 1983-09-06 US claimed
EP-1802697-B1 ADDITIVE PACKAGE FOR THERMOPLASTIC CONDENSATION POLYMERS DU PONT (US) 2011-07-20 EP disclosed
EP-2264095-A1 Additive package for thermoplastic condensation polymers E. I. du Pont de Nemours and Company (US) 2010-12-22 EP disclosed
US-7544387-B2 Additive package for thermoplastic condensation polymers THE CHEMOURS COMPANY FC, LLC 2009-06-09 US disclosed
US-20070299184-A1 Additive Package for Thermoplastic Condensation Polymers THE CHEMOURS COMPANY FC, LLC 2007-12-27 US disclosed
EP-1802697-A4 ADDITIVE PACKAGE FOR THERMOPLASTIC CONDENSATION POLYMERS DU PONT (US) 2007-10-24 EP disclosed
EP-1802697-A2 ADDITIVE PACKAGE FOR THERMOPLASTIC CONDENSATION POLYMERS E.I. DUPONT DE NEMOURS AND COMPANY (US) 2007-07-04 EP disclosed
EP-1564235-B1 Biodegradable film NIPPON CATALYTIC CHEM IND (JP) 2007-04-11 EP disclosed
WO-2006045086-A2 ADDITIVE PACKAGE FOR THERMOPLASTIC CONDENSATION POLYMERS E.I. DUPONT DE NEMOURS AND COMPANY (US) 2006-04-27 WO disclosed
US-20050182204-A1 Biodegradable film NIPPON SHOKUBAI CO., LTD. (JP) 2005-08-18 US disclosed
EP-0718366-B1 Polyester resin composition NIPPON CATALYTIC CHEM IND (JP) 2002-09-11 EP disclosed
US-20020006973-A1 Biodegradable recycled polyester resin and production process therefor NIPPON SHOKUBAI CO., LTD. 2002-01-17 US disclosed
EP-1160269-A2 Biodegradable recycled polyester resin and production process therefor Nippon Shokubai Co., Ltd. (JP) 2001-12-05 EP disclosed
EP-1148074-A2 Process for producing aliphatic polyester NIPPON SHOKUBAI CO., LTD. (JP) 2001-10-24 EP disclosed
US-5843573-A Polyester resin composition NIPPON SHOKUBAI CO., LTD. (JP) 1998-12-01 US disclosed
US-5616681-A CARRYING OUT RING-OPENING POLYMERIZATION OF CYCLIC ACID ANHYDRIDE WITH CYCLIC ETHER IN PRESENCE OF ZIRCONIUM COMPOUND NIPPON SHOKUBAI CO., LTD. (JP) 1997-04-01 US disclosed
EP-0718366-A2 Polyester resin composition NIPPON SHOKUBAI CO., LTD. (JP) 1996-06-26 EP disclosed
EP-0710685-A2 Process for producing aliphatic polyester NIPPON SHOKUBAI CO., LTD. (JP) 1996-05-08 EP disclosed
US-4403049-A POLYMERIZING A SPINNING OIL OF EPOXY COMPOUND, AN ETHYLENE UREA UNITIKA LIMITED (JP) 1983-09-06 US disclosed
US-3947428-A BIS- OR TRIS-N,N-ETHYLENEUREA PROMOTER MITSUBOSHI BELTING LTD. (JA) 1976-03-30 US disclosed