SCHEMBL8205304

SCHEMBL8205304

CCCCCCCCCCCCCCCCCCCCCCNC(=O)c1ccccc1C

nearest known ligand 0.72

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 3/20 0.72
TSHR P16473 1/20 0.70
HTT P42858 1/20 0.70
HPGD P15428 6/20 0.68
SMN1; SMN2 Q16637 4/20 0.68
ALDH1A1 P00352 1/20 0.60
LMNA P02545 1/20 0.60
HDAC3 O15379 1/20 0.59
PTGS2 P35354 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
NPC1 O15118 1/20 0.56
RAB9A P51151 1/20 0.56
KMT2A Q03164 2/20 0.56
HCRTR1 O43613 1/20 0.55
MEN1 O00255 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13293962 1.00 NAAA (0.72) NAAATSHRHTTHPGDSMN1; SMN2
SCHEMBL11291380 1.00 NAAA (0.72) NAAATSHRHTTHPGDSMN1; SMN2
SCHEMBL13310254 1.00 NAAA (0.72) NAAATSHRHTTHPGDSMN1; SMN2
SCHEMBL10330496 0.98 TSHR (0.72) NAAATSHRHTTHPGDSMN1; SMN2
SCHEMBL486382 0.93 TSHR (0.80) NAAATSHRHTTHPGDSMN1; SMN2
SCHEMBL9492896 0.93 HPGD (0.77) NAAATSHRHTTHPGDSMN1; SMN2
SCHEMBL9260536 0.90 HTT (0.86) NAAATSHRHTTHPGDSMN1; SMN2
SCHEMBL5362359 0.90 HTT (0.86) NAAATSHRHTTHPGDSMN1; SMN2
SCHEMBL11078107 0.90 HTT (0.86) NAAATSHRHTTHPGDSMN1; SMN2
SCHEMBL11089468 0.90 HTT (0.86) NAAATSHRHTTHPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6117562-A A THERMAL IMAGE TRANSFER INK LAYER FORMED ON THE SUPPORT; INK LAYER COMPRISING A COLORING AGENT, A RESIN AND A PLASTICIZER FOR LOWERING THE MELT VISCOSITY OF RESIN RICOH COMPANY, LTD. (JP) 2000-09-12 US disclosed
US-5716477-A CONSISTS OF A SUPPORT AND THERMAL IMAGE TRANSFER INK LAYER FORMED ON SAID SUPPORT CONSISTS OF A COLORING AGENT AND A PLASTICIZER FOR LOWERING MELT VISCOSITY OF THE RESIN, HIGH THERMOSENSITIVITY ON CLOTH, PLASTIC, OR PAPER RECEIVER RICOH COMPANY, LTD. (JP) 1998-02-10 US disclosed
US-4609928-A LEUCO DYES, COLOR DEVELOPERS, BISHENOL, P-HYDROXYBENZOIC ACID ESTER, POROSITY, FILLERS RICOH COMPANY, LTD. (JP) 1986-09-02 US disclosed
US-4575734-A LEVCO DYES RICOH COMPANY, LTD. (JP) 1986-03-11 US disclosed
US-4562448-A Heat-sensitive transfer medium RICOH CO., LTD. (JP) 1985-12-31 US disclosed
US-4547788-A SHEET HAVING LAYER CONTAINING LEVCO DYE; ACCEPTOR SHEET CONTAININGCOLORING AGENT; POROUS FILLER RICOH COMPANY, LTD. (JP) 1985-10-15 US disclosed
US-4352860-A Thermosensitive recording material RICOH COMPANY, LTD. (JP) 1982-10-05 US disclosed