Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.80 |
| ▸ | HTT | P42858 | 1/20 | 0.80 |
| ▸ | HPGD | P15428 | 7/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.69 |
| ▸ | NAAA | Q02083 | 2/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10330496 | 0.95 | TSHR (0.72) | TSHRHTTHPGDSMN1; SMN2NAAA | |
| SCHEMBL11291380 | 0.93 | NAAA (0.72) | TSHRHTTHPGDSMN1; SMN2NAAA | |
| SCHEMBL13293962 | 0.93 | NAAA (0.72) | TSHRHTTHPGDSMN1; SMN2NAAA | |
| SCHEMBL13310254 | 0.93 | NAAA (0.72) | TSHRHTTHPGDSMN1; SMN2NAAA | |
| SCHEMBL8205304 | 0.93 | NAAA (0.72) | TSHRHTTHPGDSMN1; SMN2NAAA | |
| SCHEMBL9492896 | 0.89 | HPGD (0.77) | TSHRHTTHPGDSMN1; SMN2NAAA | |
| SCHEMBL461599 | 0.89 | HPGD (0.64) | TSHRHTTHPGDSMN1; SMN2NAAA | |
| SCHEMBL31686014 | 0.89 | HPGD (0.64) | TSHRHTTHPGDSMN1; SMN2NAAA | |
| SCHEMBL19210845 | 0.89 | TSHR (1.00) | TSHRHTTHPGDSMN1; SMN2NAAA | |
| SCHEMBL13162414 | 0.86 | HPGD (0.69) | TSHRHTTHPGDSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992011307-A1 | LATENT, HEAT-CURABLE EPOXY RESIN COMPOSITIONS CONTAINING METAL CARBOXYLATE CURING SYSTEMS | HENKEL RESEARCH CORPORATION (US) | 1992-07-09 | — | — | WO | claimed |
| EP-3919466-A1 | MANGANESE BASED COMPLEXES AND USES THEREOF FOR HOMOGENEOUS CATALYSIS | Yeda Research and Development Co. Ltd (IL) | 2021-12-08 | — | — | EP | disclosed |
| WO-2021068773-A1 | GROUP OF TETRAHYDROINDOLOQUINAZOLINE COMPOUNDS AND USE THEREOF | 中国医学科学院医药生物技术研究所 | 2021-04-15 | — | — | WO | disclosed |
| WO-2020027304-A1 | NOVEL CAROTENOID-RELATED DERIVATIVES, AND SALTS, ESTERS, OR AMIDES THEREOF | アスタファーマシューティカルズ株式会社 | 2020-02-06 | — | — | WO | disclosed |
| EP-3039155-B1 | MOLECULE DETECTION USING BORONIC ACID SUBSTITUTED PROBES | ONTERA INC (US) | 2019-10-09 | — | — | EP | disclosed |
| WO-2015031399-A1 | MOLECULE DETECTION USING BORONIC ACID SUBSTITUTED PROBES | Two Pore Guys, Inc. (US) | 2015-03-05 | — | — | WO | disclosed |
| US-8816070-B2 | Triazole derivative as an HSP 90 inhibitor | MERCK PATENT GMBH (DE) | 2014-08-26 | — | — | US | disclosed |
| EP-2206707-B1 | AZOLECARBOXAMIDE COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC (JP) | 2014-07-23 | — | — | EP | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| EP-2411384-A1 | INSECTICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2012-02-01 | — | — | EP | disclosed |
| US-20100249088-A1 | AZOLECARBOXAMIDE COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2010-09-30 | — | — | US | disclosed |
| WO-2010108733-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2010-09-30 | — | — | WO | disclosed |
| EP-2206707-A1 | AZOLECARBOXAMIDE COMPOUND OR SALT THEREOF | Astellas Pharma Inc. (JP) | 2010-07-14 | — | — | EP | disclosed |
| US-20100113542-A1 | TRIAZOLE DERIVATIVE AS AN HSP 90 INHIBITOR | MERCK PATENT GESELLSCHAFT (DE) | 2010-05-06 | — | — | US | disclosed |
| CN-1202106-A | Selective beta 3 adrenergic agonists | LILLY CO ELI (US) | 1998-12-16 | — | — | CN | disclosed |
| US-5017686-A | Production of aromatic polyamide using a fused ring stabilizer | HUELS AKTIENGESELLSCHAFT (DE) | 1991-05-21 | — | — | US | disclosed |
| US-5015680-A | Production of a thermoplastically processable, aromatic polyamide using a 4-phenoxypyridine stabilizer | HUELS AKTIENGESELLSCHAFT (DE) | 1991-05-14 | — | — | US | disclosed |
| US-4952662-A | Molding compounds comprising a thermoplastically processible, aromatic polyamide | Huels Aktiengaellscaft (DE) | 1990-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113542-A1 | TRIAZOLE DERIVATIVE AS AN HSP 90 INHIBITOR | HSP90AB1, HSP90AB2P, HSP90AA1 | TSHR 3499/4885HTT 337/4885HPGD 959/4885 |
| US-20100249088-A1 | AZOLECARBOXAMIDE COMPOUND OR SALT THEREOF | TRPV1, FGFR3, GPR17 | TSHR 1097/4885HTT 3933/4885HPGD 1224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.