Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 8/20 | 0.52 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.52 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.52 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8216124 | 0.99 | KCNH2 (0.51) | KCNH2CACNA1FCHRM2ACHEAGTR1 | |
| Hydrochloric Acid SCHEMBL8216596 | 0.87 | KCNH2 (0.50) | KCNH2CACNA1FCHRM2ACHEAGTR1 | |
| SCHEMBL6140360 | 0.87 | KCNH2 (0.50) | KCNH2CACNA1FCHRM2ACHEAGTR1 | |
| SCHEMBL8214024 | 0.82 | SCN8A (0.47) | DRD3MAPK1ALDH1A1LMNAHTT | |
| Hydrochloric Acid SCHEMBL8214038 | 0.81 | KCNH2 (0.48) | KCNH2CACNA1FCHRM2ACHEAGTR1 | |
| SCHEMBL8205300 | 0.80 | SIGMAR1 (0.40) | KCNH2CACNA1FCACNA1DCACNA1SCACNA1C | |
| Hydrochloric Acid SCHEMBL8205350 | 0.80 | KCNH2 (0.49) | KCNH2CACNA1FCHRM2ACHEAGTR1 | |
| Hydrochloric Acid SCHEMBL7702945 | 0.80 | KCNH2 (0.70) | KCNH2CACNA1FCHRM2ACHEAGTR1 | |
| SCHEMBL8214793 | 0.80 | KCNH2 (0.49) | KCNH2KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL8203613 | 0.79 | HRH3 (0.43) | CYP1A2CYP3A4CYP2C9MAPK1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1037871-A1 | NOVEL ANTIARRHYTHMIC COMPOUNDS | GYOGYSZERKUTATO INTEZET KFT. (HU) | 2000-09-27 | — | — | EP | claimed |
| WO-1999029655-A1 | NOVEL ANTIARRHYTHMIC COMPOUNDS | Gyógyszerkutató Intézet Kft. (HU) | 1999-06-17 | — | — | WO | claimed |