Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 9/20 | 0.63 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | RXRA | P19793 | 1/20 | 0.49 |
| ▸ | RXRB | P28702 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | PLK1 | P53350 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | BCL2 | P10415 | 1/20 | 0.45 |
| ▸ | RARB | P10826 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2776629 | 0.94 | GSK3B (0.63) | GSK3BPTPN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL689331 | 0.85 | GSK3B (0.83) | GSK3BPTPN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL13815072 | 0.84 | SMN1; SMN2 (0.68) | ALDH1A1RXRARXRBMAPTSMN1; SMN2 | |
| SCHEMBL13675283 | 0.82 | ALDH1A1 (0.55) | ALDH1A1RXRARXRBMAPTSMN1; SMN2 | |
| SCHEMBL8205823 | 0.82 | RARB (0.68) | GSK3BPTPN1ALDH1A1MAPTPLK1 | |
| SCHEMBL15395891 | 0.82 | GSK3B (0.70) | GSK3BPTPN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6510438 | 0.81 | ALDH1A1 (0.53) | ALDH1A1RXRARXRBMAPTSMN1; SMN2 | |
| SCHEMBL12285881 | 0.81 | ALDH1A1 (0.53) | GSK3BALDH1A1RXRARXRBMAPT | |
| SCHEMBL18209648 | 0.80 | GSK3B (0.68) | GSK3BPTPN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8213015 | 0.80 | GSK3B (0.88) | GSK3BPTPN1ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1031349-A1 | Use of substituted 4-biarylbutyric and 5-biarylpentanoic acid derivatives for the treatment of cerebral diseases | Bayer Aktiengesellschaft (DE) | 2000-08-30 | — | — | EP | disclosed |