Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | RXRA | P19793 | 1/20 | 0.50 |
| ▸ | RXRB | P28702 | 1/20 | 0.50 |
| ▸ | PLK1 | P53350 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | BCL2 | P10415 | 1/20 | 0.46 |
| ▸ | RARB | P10826 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8122311 | 0.94 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2MAPTL3MBTL1RXRA | |
| SCHEMBL13815072 | 0.86 | SMN1; SMN2 (0.68) | ALDH1A1SMN1; SMN2MAPTL3MBTL1RXRA | |
| SCHEMBL13675346 | 0.83 | BCL2 (0.71) | ALDH1A1SMN1; SMN2MAPTL3MBTL1RXRA | |
| SCHEMBL6510438 | 0.82 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2MAPTL3MBTL1RXRA | |
| SCHEMBL8205338 | 0.82 | GSK3B (0.63) | ALDH1A1SMN1; SMN2MAPTL3MBTL1RXRA | |
| SCHEMBL12285881 | 0.82 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2MAPTL3MBTL1RXRA | |
| SCHEMBL9420265 | 0.81 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2MAPTRXRARXRB | |
| SCHEMBL11135890 | 0.81 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2MAPTL3MBTL1RXRA | |
| SCHEMBL23512472 | 0.79 | SMN1; SMN2 (0.68) | ALDH1A1SMN1; SMN2MAPTL3MBTL1RXRA | |
| SCHEMBL13814812 | 0.79 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2MAPTL3MBTL1RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101640-B2 | Antibacterial agents | NOVARTIS VACCINES AND DIAGNOSTICS, INC. (US) | 2012-01-24 | — | — | US | disclosed |
| US-20110172174-A1 | Antibacterial agents | NOVARTIS VACCINES AND DIAGNOSTICS INC. | 2011-07-14 | — | — | US | disclosed |
| US-20090270381-A1 | Non-steroidal progesterone receptor modulators | BAYER SCHERING PHARMA AG (DE) | 2009-10-29 | — | — | US | disclosed |
| WO-2009077186-A1 | NONSTEROIDAL PROGESTERONE RECEPTOR MODULATORS | BAYER SCHERING PHARMA AKTIENGESLLSCHAFT (DE) | 2009-06-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270381-A1 | Non-steroidal progesterone receptor modulators | PGR, PGRMC1, PGRMC2 | ALDH1A1 1257/4885SMN1; SMN2 3946/4885MAPT 4869/4885 |
| US-20110172174-A1 | Antibacterial agents | MRPL21, SI, PGLS | ALDH1A1 782/4885SMN1; SMN2 2296/4885MAPT 4619/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.