Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPI | P34949 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Mannose 6-Phosphate SCHEMBL8205373 | 0.86 | MPI (0.55) | MPI | |
| SCHEMBL9117419 | 0.83 | MPI (0.58) | MPI | |
| SCHEMBL987653 | 0.83 | MPI (0.58) | MPI | |
| SCHEMBL523990 | 0.83 | MPI (0.58) | MPI | |
| SCHEMBL6151201 | 0.83 | MPI (0.34) | MPI | |
| SCHEMBL873894 | 0.83 | MPI (0.34) | MPI | |
| SCHEMBL5921670 | 0.82 | MPI (0.45) | MPI | |
| SCHEMBL3487364 | 0.82 | MPI (0.45) | MPI | |
| SCHEMBL11889064 | 0.81 | MPI (0.35) | MPI | |
| Methoxyamine SCHEMBL6040185 | 0.80 | MPI (0.51) | MPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6011001-A | Method of protein therapy by orally administering crosslinked protein crystals | VERTEX PHARMACEUTICALS, INC. (US) | 2000-01-04 | — | — | US | disclosed |
| US-6004768-A | Biosensors, extracorporeal devices and methods for detecting substances using crosslinked protein crystals | VERTEX PHARMACEUTICALS, INC. (US) | 1999-12-21 | — | — | US | disclosed |
| US-5976529-A | Methods of enzyme therapy by orally administering crosslinked enzyme crystals | VERTEX PHARMACEUTICALS, INC. (US) | 1999-11-02 | — | — | US | disclosed |
| US-5849296-A | Crosslinked protein crystals | VERTEX PHARMACEUTICALS, INC. (US) | 1998-12-15 | — | — | US | disclosed |
| US-5618710-A | RESISTANCE TO EXOGENOUS PROTEOLYSIS | VERTEX PHARMACEUTICALS, INC. (US) | 1997-04-08 | — | — | US | disclosed |