Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.34 |
| ▸ | DPP4 | P27487 | 4/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.34 |
| ▸ | FAP | Q12884 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 2/20 | 0.30 |
| ▸ | NOS1 | P29475 | 2/20 | 0.30 |
| ▸ | NOS2 | P35228 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL27639977 | 0.97 | GSR (0.47) | GSRDPP7DPP4DPP8DPP9 | |
| Lysine SCHEMBL659927 | 0.97 | GSR (0.47) | GSRDPP7DPP4DPP8DPP9 | |
| Lysine SCHEMBL17685564 | 0.94 | GSR (0.43) | GSRDPP7DPP4DPP8DPP9 | |
| Lysine SCHEMBL9721034 | 0.92 | GSR (0.44) | GSRDPP7DPP4DPP8DPP9 | |
| Lysine SCHEMBL1675278 | 0.92 | GSR (0.44) | GSRDPP7DPP4DPP8DPP9 | |
| Lysine SCHEMBL4254655 | 0.92 | GSR (0.44) | GSRDPP7DPP4DPP8DPP9 | |
| Lysine SCHEMBL29054307 | 0.92 | GSR (0.40) | GSRDPP7DPP4DPP8DPP9 | |
| Glutamine SCHEMBL10610949 | 0.92 | GSR (0.36) | GSR | |
| Lysine SCHEMBL18263286 | 0.91 | GSR (0.48) | GSRDPP7DPP4DPP8DPP9 | |
| Lysine SCHEMBL18259132 | 0.91 | GSR (0.48) | GSRDPP7DPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015595-A1 | PEPTIDES DERIVED FROM THE ATTACHMENT (G) PROTEIN OF RESPIRATORY SYNCYTIAL VIRUS | AMERICAN CYANAMID COMPANY (US) | 2000-07-05 | — | — | EP | claimed |
| WO-1999014334-A1 | PEPTIDES DERIVED FROM THE ATTACHMENT (G) PROTEIN OF RESPIRATORY SYNCYTIAL VIRUS | AMERICAN CYANAMID COMPANY (US) | 1999-03-25 | — | — | WO | claimed |