Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 4/20 | 0.70 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL111796 | 0.87 | TRPA1 (0.47) | TRPA1GRIK1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8207850 | 0.84 | TRPA1 (0.69) | TRPA1KCNH2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL295543 | 0.83 | TRPA1 (1.00) | TRPA1LMNA | |
| SCHEMBL28973918 | 0.82 | SIGMAR1 (0.46) | TRPA1CYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL17027838 | 0.80 | TRPA1 (0.47) | TRPA1 | |
| SCHEMBL17027762 | 0.80 | TRPA1 (0.47) | TRPA1 | |
| SCHEMBL4557581 | 0.80 | TRPA1 (0.47) | TRPA1 | |
| SCHEMBL17027833 | 0.80 | TRPA1 (0.47) | TRPA1 | |
| SCHEMBL17027702 | 0.80 | TRPA1 (0.47) | TRPA1 | |
| SCHEMBL17027859 | 0.80 | TRPA1 (0.47) | TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0989970-A1 | FRAGRANCE PRECURSOR COMPOUNDS | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 2000-04-05 | — | — | EP | disclosed |
| WO-1998058899-A1 | FRAGRANCE PRECURSOR COMPOUNDS | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 1998-12-30 | — | — | WO | disclosed |