Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 8/20 | 0.40 |
| ▸ | FNTB | P49356 | 8/20 | 0.40 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8206389 | 0.91 | FNTA (0.46) | CA2CA1ALDH1A1USP2TP53 | |
| SCHEMBL8198280 | 0.91 | FNTA (0.46) | CA2CA1ALDH1A1USP2TP53 | |
| SCHEMBL8207254 | 0.88 | FNTA (0.47) | FNTAFNTB | |
| SCHEMBL8199776 | 0.87 | FNTA (0.49) | FNTAFNTB | |
| SCHEMBL8209847 | 0.86 | FNTA (0.41) | ALDH1A1FNTAFNTBPGGT1BNPSR1 | |
| SCHEMBL8199385 | 0.85 | FNTA (0.52) | FNTAFNTB | |
| SCHEMBL8209147 | 0.84 | FNTA (0.40) | CA2CA1CA12CA9KMT2A | |
| SCHEMBL8211056 | 0.83 | FNTA (0.40) | ALDH1A1FNTAFNTBPGGT1BGAA | |
| SCHEMBL8198655 | 0.82 | FNTA (0.41) | FNTAFNTB | |
| SCHEMBL8209424 | 0.80 | FNTA (0.43) | FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975603-A1 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | ZENECA LIMITED (GB) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998032741-A1 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | ZENECA LIMITED (GB) | 1998-07-30 | — | — | WO | disclosed |