SCHEMBL8205651

SCHEMBL8205651

O=c1c(O)ccc2oc3ccccc3nc1-2

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.46
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46
MITF O75030 1/20 0.46
KDM6B O15054 1/20 0.44
KDM6A O15550 1/20 0.44
RAB9A P51151 4/20 0.43
ALDH1A1 P00352 4/20 0.43
ALPL P05186 2/20 0.43
ALPG P10696 2/20 0.43
KDM4E B2RXH2 2/20 0.43
POLB P06746 1/20 0.43
ALPI P09923 1/20 0.43
RECQL P46063 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
APP P05067 1/20 0.43
NR1I2 O75469 1/20 0.42
CHRM1 P11229 1/20 0.42
DRD2 P14416 1/20 0.42
ADRA2B P18089 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28570620 0.81 MAPT (0.46) MAPTMEN1KMT2AMITFRAB9A
SCHEMBL1635786 0.81 MAPT (0.54) MAPTMEN1KMT2AMITFRAB9A
SCHEMBL3494874 0.77 MAPT (0.44) MAPTMEN1KMT2AMITFRAB9A
SCHEMBL1635805 0.76 RAB9A (0.49) MAPTMEN1KMT2ARAB9AALDH1A1
SCHEMBL306543 0.75 MAPT (0.50) MAPTMEN1KMT2AMITFRAB9A
SCHEMBL29631752 0.75 MAPT (0.50) MAPTMEN1KMT2AMITFRAB9A
SCHEMBL28560105 0.74 MAPT (0.44) MAPTMEN1KMT2AMITFALDH1A1
Hydrochloric Acid SCHEMBL10485854 0.73 MAPT (0.49) MAPTMEN1KMT2AMITFRAB9A
SCHEMBL1550910 0.73 MAPT (0.46) MAPTMEN1KMT2AMITFRAB9A
SCHEMBL5492954 0.72 ELANE (0.45) MAPTMEN1KMT2AMITFL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0396642-B1 ENZYME CONTROLLED RELEASE SYSTEM POLAROID CORP (US) 1994-05-11 EP claimed
US-5112739-A Quinone-methide elimination POLAROID CORPORATION (US) 1992-05-12 US claimed
EP-0396642-A1 ENZYME CONTROLLED RELEASE SYSTEM. POLAROID CORP (US) 1990-11-14 EP claimed
WO-1990001558-A1 ENZYME CONTROLLED RELEASE SYSTEM POLAROID CORPORATION (US) 1990-02-22 WO claimed
CN-117897454-A Dibenzoxanthene quencher, use and preparation method 生命技术公司 2024-04-16 CN disclosed
US-20240011099-A1 STAINED BIOLOGICAL SPECIMENS INCLUDING ONE OR MORE BIOMARKERS LABELED WITH ONE OR MORE DETECTABLE MOIETIES VENTANA MED SYST INC (US) 2024-01-11 US disclosed
EP-4281779-A1 STAINED BIOLOGICAL SPECIMENS INCLUDING ONE OR MORE BIOMARKERS LABELED WITH ONE OR MORE DETECTABLE MOIETIES Ventana Medical Systems, Inc. (US) 2023-11-29 EP disclosed
CN-116868054-A Stained biological samples comprising one or more biomarkers labeled with one or more detectable moieties 文塔纳医疗系统公司 2023-10-10 CN disclosed
US-6096144-A TREATING WITH ACIDIC OR ALKALINE SOLUTION OF CONJUGATED UNSATURATED COMPOUND WITH AT LEAST 5 BONDS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-08-01 US disclosed
US-5858571-A TREATING A PULVERIZED HYDROGEN ABSORBING ALLOY WITH A SOLUTION COMPRISING A CONJUGATED UNSATURATED COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-01-12 US disclosed
EP-0614530-B1 INDIRECT IMMUNOASSAY FOR DIOXINLIKE COMPOUNDS CORNELL RES FOUNDATION INC (US) 1998-03-04 EP disclosed
US-5496703-A DETECTING POLYCHLORINATED DIBENZODIOXINS, POLYCHLORINATED DIBENZOFURANS CORNELL RESEARCH FOUNDATION, INC. (US) 1996-03-05 US disclosed
US-5242805-A Useful in directingcells producing enzymes that hydrolyze the glycoside MOLECULAR PROBES, INC. (US) 1993-09-07 US disclosed
WO-1993010460-A1 INDIRECT IMMUNOASSAY FOR DIOXINLIKE COMPOUNDS CORNELL RESEARCH FOUNDATION, INC. (US) 1993-05-27 WO disclosed
WO-1993004074-A1 LONG WAVELENGTH LIPOPHILIC FLUOROGENIC GLYCOSIDASE SUBSTRATES MOLECULAR PROBES, INC. (US) 1993-03-04 WO disclosed
US-5112739-A Quinone-methide elimination POLAROID CORPORATION (US) 1992-05-12 US disclosed
EP-0396642-A1 ENZYME CONTROLLED RELEASE SYSTEM. POLAROID CORP (US) 1990-11-14 EP disclosed
WO-1990001558-A1 ENZYME CONTROLLED RELEASE SYSTEM POLAROID CORPORATION (US) 1990-02-22 WO disclosed
US-4539230-A COATING WALLS WITH A CHELATE COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 1985-09-03 US disclosed
EP-0126991-A1 A method for preventing deposition of polymer scale and a coating agent therefor Shin-Etsu Chemical Co., Ltd. (JP) 1984-12-05 EP disclosed