SCHEMBL1635786

SCHEMBL1635786

Nc1ccc2oc3ccccc3nc-2c1=O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.54
MEN1 O00255 5/20 0.54
KMT2A Q03164 5/20 0.54
RAB9A P51151 5/20 0.54
POLB P06746 3/20 0.54
ALDH1A1 P00352 3/20 0.54
KDM4E B2RXH2 2/20 0.54
ALPL P05186 1/20 0.54
ALPI P09923 1/20 0.54
ALPG P10696 1/20 0.54
RECQL P46063 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
MITF O75030 1/20 0.46
NPC1 O15118 4/20 0.41
ATM Q13315 1/20 0.41
GAA P10253 3/20 0.40
LMNA P02545 2/20 0.40
ALOX15 P16050 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
ADRA2C P18825 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1550910 0.90 MAPT (0.46) MAPTMEN1KMT2ARAB9APOLB
SCHEMBL28570620 0.81 MAPT (0.46) MAPTMEN1KMT2ARAB9APOLB
SCHEMBL8205651 0.81 MAPT (0.46) MAPTMEN1KMT2ARAB9APOLB
SCHEMBL3494874 0.77 MAPT (0.44) MAPTMEN1KMT2ARAB9APOLB
SCHEMBL10941393 0.77 MEN1 (0.51) MAPTMEN1KMT2ARAB9APOLB
SCHEMBL29631752 0.75 MAPT (0.50) MAPTMEN1KMT2ARAB9APOLB
SCHEMBL306543 0.75 MAPT (0.50) MAPTMEN1KMT2ARAB9APOLB
SCHEMBL28560105 0.74 MAPT (0.44) MAPTMEN1KMT2AALDH1A1MITF
Hydrochloric Acid SCHEMBL10485854 0.73 MAPT (0.49) MAPTMEN1KMT2ARAB9APOLB
SCHEMBL3276944 0.73 MEN1 (0.56) MAPTMEN1KMT2ARAB9APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009003625-A1 AMINOPHENOXAZINONE AS AN ANTI-TUMOUR AND ANTI-INFLAMMATORY AGENT EBERHARD-KARLS-UNIVERSITAET TUEBINGEN UNIVERSITAETSKILINIKUM (DE) 2009-01-08 WO claimed
US-5693442-A ELEMENT HAVING OVERCOAT OVERLYING CHARGE GENERATING LAYER COMPRISING DYE AND/OR ORGANIC PIGMENT AND COMPLEX OF INORGANIC OXIDE POLYMER AND CHARGE CARRIER EASTMAN KODAK COMPANY (US) 1997-12-02 US claimed
CN-119118944-A Near infrared fluorescent small molecular probe and preparation method and application thereof 南京科技职业学院 2024-12-13 CN disclosed
CN-113441135-B Preparation method of 2-amino-3H-phenoxazin-3-one or derivative thereof 兰州大学 2022-09-20 CN disclosed
CN-113441135-A Preparation method of 2-amino-3H-phenoxazin-3-one or derivative thereof 兰州大学 2021-09-28 CN disclosed
US-20160200769-A1 Compound, Transitmycin, Effective Against Bacterial and Viral Pathogens INDIAN COUNCIL OF MEDICAL RESEARCH (IN) 2016-07-14 US disclosed
WO-2015022698-A1 A COMPOUND, TRANSITMYCIN, EFFECTIVE AGAINST BACTERIAL AND VIRAL PATHOGENS INDIAN COUNCIL OF MEDICAL RESEARCH (IN) 2015-02-19 WO disclosed
US-7932050-B2 Enzymatic substrates derived from phenoxazinone and their use as developers in detection of microorganisms with peptidase activity BIOMERIEUX (FR) 2011-04-26 US disclosed
US-20100324285-A1 ANTIINFLAMMATORY AGENT COMPRISING 2-AMINOPHENOL OR DERIVATIVE THEREOF AS ACTIVE INGREDIENT KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) 2010-12-23 US disclosed
US-20100028926-A1 Novel enzymatic substrates derived from phenoxazinone and their use as developer in detection of microorganisms with peptidase activity BIOMERIEUX (FR) 2010-02-04 US disclosed
WO-2010003970-A2 PHENOXAZINE DYES Wetlands Incubator sprl (BE) 2010-01-14 WO disclosed
US-5858571-A TREATING A PULVERIZED HYDROGEN ABSORBING ALLOY WITH A SOLUTION COMPRISING A CONJUGATED UNSATURATED COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-01-12 US disclosed
EP-0872903-A1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder Shin-Etsu Chemical Co., Ltd. (JP) 1998-10-21 EP disclosed
US-5693442-A ELEMENT HAVING OVERCOAT OVERLYING CHARGE GENERATING LAYER COMPRISING DYE AND/OR ORGANIC PIGMENT AND COMPLEX OF INORGANIC OXIDE POLYMER AND CHARGE CARRIER EASTMAN KODAK COMPANY (US) 1997-12-02 US disclosed
US-4861775-A Pharmacological use of phenoxazinones HOECHST AKTIENGESELLSCHAFT (DE) 1989-08-29 US disclosed
EP-0172427-B1 PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER Shin-Etsu Chemical Co., Ltd. (JP) 1989-07-05 EP disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
EP-0260486-A1 Pharmacologically active phenoxazinones, process for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1988-03-23 EP disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100324285-A1 ANTIINFLAMMATORY AGENT COMPRISING 2-AMINOPHENOL OR DERIVATIVE THEREOF AS ACTIVE INGREDIENT PTGES2, PTGS2, PTGES MAPT 2218/4885MEN1 4848/4885KMT2A 1434/4885
US-20160200769-A1 Compound, Transitmycin, Effective Against Bacterial and Viral Pathogens MAVS, TIMM50, TREH MAPT 583/4885MEN1 1882/4885KMT2A 3618/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.