SCHEMBL8205653

SCHEMBL8205653

O=NOc1ccc(O)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
ESR2 Q92731 2/20 0.50
ESR1 P03372 1/20 0.50
LTA4H P09960 3/20 0.42
NR1H2 P55055 1/20 0.42
BAX Q07812 1/20 0.42
KDM4E B2RXH2 3/20 0.42
MAPT P10636 2/20 0.42
BLM P54132 2/20 0.42
LMNA P02545 2/20 0.42
HIF1A Q16665 2/20 0.42
NPC1 O15118 1/20 0.42
CA12 O43570 1/20 0.42
GMNN O75496 1/20 0.42
ALDH1A1 P00352 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA3 P07451 1/20 0.42
CYP3A4 P08684 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27666939 0.75 KMT2A (0.52) MEN1KMT2AMAPTLMNAALDH1A1
SCHEMBL2186812 0.74 BACE1 (0.42) NPC1CA12CA1CA2CA3
SCHEMBL27856948 0.74 CA2 (0.43) MEN1KMT2AMAPTLMNANPC1
SCHEMBL27516836 0.74 MEN1 (0.43) MEN1KMT2AMAPTLMNACA12
SCHEMBL17315654 0.74 CA1 (0.58) KDM4EMAPTNPC1CA12ALDH1A1
SCHEMBL5320665 0.74 TDP1 (0.50) MEN1KMT2AKDM4EMAPTBLM
SCHEMBL18392231 0.74 ESR2 (0.50) MEN1KMT2AESR2ESR1LTA4H
SCHEMBL27317185 0.74
SCHEMBL27761719 0.74 SOS1 (0.39) MEN1KMT2ALMNACA12ALDH1A1
SCHEMBL27989835 0.74 CA1 (0.43) CA12CA1CA2CA9APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1372452-A UV radiation reflecting or absorbing agent for protection against harmful UV radiation and for enhancing natural skin barrier PHARMASOL GMBH (DE) 2002-10-02 CN claimed
US-20240011099-A1 STAINED BIOLOGICAL SPECIMENS INCLUDING ONE OR MORE BIOMARKERS LABELED WITH ONE OR MORE DETECTABLE MOIETIES VENTANA MED SYST INC (US) 2024-01-11 US disclosed
EP-4281779-A1 STAINED BIOLOGICAL SPECIMENS INCLUDING ONE OR MORE BIOMARKERS LABELED WITH ONE OR MORE DETECTABLE MOIETIES Ventana Medical Systems, Inc. (US) 2023-11-29 EP disclosed
WO-2020231333-A1 TYROSINASE INHIBITORS AND THEIR USES NATIONAL UNIVERSITY OF SINGAPORE (SG) 2020-11-19 WO disclosed
CN-1372452-A UV radiation reflecting or absorbing agent for protection against harmful UV radiation and for enhancing natural skin barrier PHARMASOL GMBH (DE) 2002-10-02 CN disclosed
CN-1324610-A Use of sunblock composition using aminohydrox-diphenyl methanone as necessary components in light-stabilizing UV filtering agent, in cosmetics and medicines BASF AG (DE) 2001-12-05 CN disclosed
US-6096144-A TREATING WITH ACIDIC OR ALKALINE SOLUTION OF CONJUGATED UNSATURATED COMPOUND WITH AT LEAST 5 BONDS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-08-01 US disclosed
CN-1218661-A Cosmetics and medicine containing light stable ultraviolet filter agent BASF AG (DE) 1999-06-09 CN disclosed
US-5858571-A TREATING A PULVERIZED HYDROGEN ABSORBING ALLOY WITH A SOLUTION COMPRISING A CONJUGATED UNSATURATED COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-01-12 US disclosed
EP-0614530-B1 INDIRECT IMMUNOASSAY FOR DIOXINLIKE COMPOUNDS CORNELL RES FOUNDATION INC (US) 1998-03-04 EP disclosed
US-5496703-A DETECTING POLYCHLORINATED DIBENZODIOXINS, POLYCHLORINATED DIBENZOFURANS CORNELL RESEARCH FOUNDATION, INC. (US) 1996-03-05 US disclosed
EP-0614530-A4 INDIRECT IMMUNOASSAY FOR DIOXINLIKE COMPOUNDS. CORNELL RES FOUNDATION INC (US) 1995-06-07 EP disclosed
EP-0614530-A1 INDIRECT IMMUNOASSAY FOR DIOXINLIKE COMPOUNDS CORNELL RESEARCH FOUNDATION, INC. (US) 1994-09-14 EP disclosed
WO-1993010460-A1 INDIRECT IMMUNOASSAY FOR DIOXINLIKE COMPOUNDS CORNELL RESEARCH FOUNDATION, INC. (US) 1993-05-27 WO disclosed
EP-0172427-B1 PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER Shin-Etsu Chemical Co., Ltd. (JP) 1989-07-05 EP disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed
US-4539230-A COATING WALLS WITH A CHELATE COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 1985-09-03 US disclosed
EP-0126991-A1 A method for preventing deposition of polymer scale and a coating agent therefor Shin-Etsu Chemical Co., Ltd. (JP) 1984-12-05 EP disclosed