Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 8/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL27482924 | 0.84 | MEN1 (0.43) | TDP1ALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL27317185 | 0.74 | — | — | |
| SCHEMBL27989835 | 0.74 | CA1 (0.43) | APP | |
| SCHEMBL9246841 | 0.74 | ACHE (0.48) | TDP1ALDH1A1CYP3A4TSHRMAPT | |
| SCHEMBL27856948 | 0.74 | CA2 (0.43) | ALDH1A1MAPK1MAOAMAPTMEN1 | |
| SCHEMBL27761719 | 0.74 | SOS1 (0.39) | ALDH1A1MAOAMEN1KMT2AMAOB | |
| SCHEMBL27516836 | 0.74 | MEN1 (0.43) | TDP1ALDH1A1CYP3A4MAPK1MAOA | |
| SCHEMBL17315654 | 0.74 | CA1 (0.58) | TDP1ALDH1A1CYP3A4MAPK1MAPT | |
| SCHEMBL8205653 | 0.74 | MEN1 (0.50) | TDP1ALDH1A1CYP3A4MAPTMEN1 | |
| SCHEMBL306544 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107778255-B | A kind of Diarylmiazines HIV-1 reverse transcriptase inhibitor and its preparation method and application | 山东大学 | 2019-10-25 | — | — | CN | claimed |
| US-5693442-A | ELEMENT HAVING OVERCOAT OVERLYING CHARGE GENERATING LAYER COMPRISING DYE AND/OR ORGANIC PIGMENT AND COMPLEX OF INORGANIC OXIDE POLYMER AND CHARGE CARRIER | EASTMAN KODAK COMPANY (US) | 1997-12-02 | — | — | US | claimed |
| CN-113121997-B | Nitrile-based resin single-component composite material recovered based on nitrile-based resin and preparation method thereof | 成都大学 | 2022-09-30 | — | — | CN | disclosed |
| CN-113121997-A | Nitrile resin single-component composite material based on nitrile resin recovery and preparation method thereof | 成都大学 | 2021-07-16 | — | — | CN | disclosed |
| CN-105606605-B | A kind of Hydroxyphenylalanineurine urine detection reagent box and preparation method | 张凤华 | 2019-09-20 | — | — | CN | disclosed |
| CN-109280179-A | A kind of covalent organic framework material and preparation method thereof and the application in hindered amines synthesis | 天罡新材料（廊坊）股份有限公司 | 2019-01-29 | — | — | CN | disclosed |
| CN-108059605-A | The synthetic method of p-aminophenyl formonitrile HCN | 江苏优普生物化学科技股份有限公司 | 2018-05-22 | — | — | CN | disclosed |
| CN-104768952-B | PI3K inhibitors | 山东亨利医药科技有限责任公司 | 2016-10-19 | — | — | CN | disclosed |
| US-20070248581-A1 | MGRA IS A REDOX REGULATOR OF ANTIBIOTIC SENSITIVITY AND VIRULENCE | THE UNIVERSITY OF CHICAGO | 2007-10-25 | — | — | US | disclosed |
| WO-2007090123-A2 | MGRA IS A REDOX REGULATOR OF ANTIBIOTIC SENSITIVITY AND VIRULENCE | UNIVERSITY OF CHICAGO (US) | 2007-08-09 | — | — | WO | disclosed |
| CN-1182203-C | Modified carbon products and amphiphilic ions containing compositions | ���Ͽع�����˾ | 2004-12-29 | — | — | CN | disclosed |
| US-6096144-A | TREATING WITH ACIDIC OR ALKALINE SOLUTION OF CONJUGATED UNSATURATED COMPOUND WITH AT LEAST 5 BONDS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2000-08-01 | — | — | US | disclosed |
| CN-1227585-A | Modified carbon products and amphiphilic ions containing compositions | CABOT CORP (US) | 1999-09-01 | — | — | CN | disclosed |
| US-5858571-A | TREATING A PULVERIZED HYDROGEN ABSORBING ALLOY WITH A SOLUTION COMPRISING A CONJUGATED UNSATURATED COMPOUND | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1999-01-12 | — | — | US | disclosed |
| EP-0872903-A1 | Method for making hydrogen storage alloy powder and electrode comprising the alloy powder | Shin-Etsu Chemical Co., Ltd. (JP) | 1998-10-21 | — | — | EP | disclosed |
| US-5693442-A | ELEMENT HAVING OVERCOAT OVERLYING CHARGE GENERATING LAYER COMPRISING DYE AND/OR ORGANIC PIGMENT AND COMPLEX OF INORGANIC OXIDE POLYMER AND CHARGE CARRIER | EASTMAN KODAK COMPANY (US) | 1997-12-02 | — | — | US | disclosed |
| EP-0172427-B1 | PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER | Shin-Etsu Chemical Co., Ltd. (JP) | 1989-07-05 | — | — | EP | disclosed |
| US-4758639-A | Process for production of vinyl polymer | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1988-07-19 | — | — | US | disclosed |
| US-4757124-A | Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0172427-A2 | Process for production of vinyl chloride polymer | Shin-Etsu Chemical Co., Ltd. (JP) | 1986-02-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070248581-A1 | MGRA IS A REDOX REGULATOR OF ANTIBIOTIC SENSITIVITY AND VIRULENCE | GFER, GLRX3, PRDX3 | TDP1 4706/4885ALDH1A1 3399/4885CYP3A4 2493/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.