Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 8/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6322881 | 0.86 | GHSR (0.54) | GHSRCYP3A4CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL6322878 | 0.86 | GHSR (0.54) | GHSRCYP3A4CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL7131016 | 0.78 | GHSR (0.54) | GHSRCYP3A4CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL7131022 | 0.78 | GHSR (0.54) | GHSRCYP3A4CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL6401403 | 0.76 | GHSR (0.51) | GHSRCYP3A4CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL6401402 | 0.76 | GHSR (0.51) | GHSRCYP3A4CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL7059991 | 0.74 | GHSR (0.39) | GHSRCYP3A4CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL6324584 | 0.73 | CYP3A4 (0.40) | GHSRCYP3A4CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL6317840 | 0.73 | GHSR (0.38) | GHSRCYP3A4CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL7161809 | 0.72 | GHSR (0.48) | GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127391-A | A PEPTIDE MIMETIC COMPOUND FOR STIMULATING THE RELEASE OF GROWTH HORMONE FROM THE PITUITARY | NOVO NORDISK A/S (DK) | 2000-10-03 | — | — | US | disclosed |