Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 3/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 4/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6317840 | 0.90 | GHSR (0.38) | GHSRMAOBCYP3A4CYP2D6SLC6A2 | |
| SCHEMBL6324584 | 0.87 | CYP3A4 (0.40) | GHSRMAOBCYP3A4CYP2D6SLC6A2 | |
| SCHEMBL6322878 | 0.86 | GHSR (0.54) | GHSRMAOBCYP3A4CYP2D6SLC6A2 | |
| SCHEMBL6322881 | 0.86 | GHSR (0.54) | GHSRMAOBCYP3A4CYP2D6SLC6A2 | |
| SCHEMBL7131022 | 0.85 | GHSR (0.54) | GHSRMAOBCYP3A4CYP2D6SLC6A2 | |
| SCHEMBL7131016 | 0.85 | GHSR (0.54) | GHSRMAOBCYP3A4CYP2D6SLC6A2 | |
| SCHEMBL6401402 | 0.82 | GHSR (0.51) | GHSRCYP3A4CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL6401403 | 0.82 | GHSR (0.51) | GHSRCYP3A4CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL6600776 | 0.77 | GHSR (0.42) | GHSRTACR1MMP9MMP8 | |
| SCHEMBL8205693 | 0.74 | GHSR (0.41) | GHSRMAOBCYP3A4CYP2D6SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030055261-A1 | Compounds with growth hormone releasing properties | HELSINN THERAPEUTICS (U.S.), INC. | 2003-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030055261-A1 | Compounds with growth hormone releasing properties | GHRHR, GHSR, IGFBP1 | GHSR 2/4885MAOB 840/4885CYP3A4 3623/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.