Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 8/20 | 0.66 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.57 |
| ▸ | TTR | P02766 | 4/20 | 0.57 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8205829 | 1.00 | PTGS1 (0.66) | PTGS1PTGS2KDM4ELMNAALOX5 | |
| SCHEMBL4202763 | 0.89 | PTGS1 (0.71) | PTGS1PTGS2KDM4ELMNAALOX5 | |
| SCHEMBL4202762 | 0.89 | PTGS1 (0.71) | PTGS1PTGS2KDM4ELMNAALOX5 | |
| SCHEMBL12913068 | 0.89 | PTGS1 (0.71) | PTGS1PTGS2KDM4ELMNAALOX5 | |
| SCHEMBL8199126 | 0.88 | PTGS2 (0.67) | PTGS1PTGS2KDM4ELMNAALOX5 | |
| SCHEMBL8199129 | 0.88 | PTGS2 (0.67) | PTGS1PTGS2KDM4ELMNAALOX5 | |
| SCHEMBL7864820 | 0.87 | APP (0.62) | PTGS1PTGS2KDM4ELMNAALOX5 | |
| SCHEMBL7905714 | 0.87 | APP (0.62) | PTGS1PTGS2KDM4ELMNAALOX5 | |
| SCHEMBL3767639 | 0.87 | APP (0.62) | PTGS1PTGS2KDM4ELMNAALOX5 | |
| SCHEMBL7864785 | 0.87 | APP (0.62) | PTGS1PTGS2KDM4ELMNAALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8176079-A | — | — | None | — | — | JP | disclosed |
| US-6066757-A | MAY BE INCORPORATED INTO PHOTOCONDUCTING LAYER OF ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR AS CHARGE TRANSPORTING MATERIAL | RICOH COMPANY, LTD. (JP) | 2000-05-23 | — | — | US | disclosed |
| US-5641598-A | HAVING HIGH RESISTANCE TO THERMAL AND MECHANICAL SHOCK | RICOH COMPANY, LTD. (JP) | 1997-06-24 | — | — | US | disclosed |
| JP-H08176079-A | DIHYDROXYSTILBENE COMPOUND AND ITS PRODUCTION | RICOH CO LTD | 1996-07-09 | — | — | JP | disclosed |