Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 15/20 | 0.72 |
| ▸ | FGFR1 | P11362 | 12/20 | 0.72 |
| ▸ | KDR | P35968 | 12/20 | 0.72 |
| ▸ | SRC | P12931 | 7/20 | 0.72 |
| ▸ | EGFR | P00533 | 4/20 | 0.72 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.50 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8205878 | 1.00 | PDGFRB (0.72) | PDGFRBFGFR1KDRSRCEGFR | |
| SCHEMBL7837476 | 0.92 | PDGFRB (0.71) | PDGFRBFGFR1KDRSRCEGFR | |
| SCHEMBL7837474 | 0.92 | PDGFRB (0.71) | PDGFRBFGFR1KDRSRCEGFR | |
| SCHEMBL8211103 | 0.85 | PDGFRB (0.72) | PDGFRBFGFR1KDRSRCEGFR | |
| SCHEMBL7825508 | 0.85 | PDGFRB (0.72) | PDGFRBFGFR1KDRSRCEGFR | |
| SCHEMBL6391952 | 0.84 | FGFR1 (1.00) | PDGFRBFGFR1KDRSRCEGFR | |
| SCHEMBL6391950 | 0.84 | FGFR1 (1.00) | PDGFRBFGFR1KDRSRCEGFR | |
| SCHEMBL7838947 | 0.82 | FGFR1 (1.00) | PDGFRBFGFR1KDRSRCEGFR | |
| SCHEMBL7838948 | 0.82 | FGFR1 (1.00) | PDGFRBFGFR1KDRSRCEGFR | |
| SCHEMBL8199244 | 0.81 | CHEK1 (0.70) | PDGFRBFGFR1KDRSRCEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999048868-A9 | HETEROCYCLIC CLASSES OF COMPOUNDS FOR THE MODULATING TYROSINE PROTEIN KINASE | SUGEN INC (US) | 2000-04-20 | — | — | WO | disclosed |