Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | BRD2 | P25440 | 1/20 | 0.44 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.44 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3175794 | 0.80 | CASP3 (0.46) | BRD4KDM4EALDH1A1POLBLMNA | |
| SCHEMBL3177116 | 0.79 | BRD4 (0.51) | BRD4KDM4EALDH1A1POLBLMNA | |
| SCHEMBL3183997 | 0.75 | KDM4E (0.38) | BRD4KDM4EALDH1A1POLBLMNA | |
| SCHEMBL13531564 | 0.73 | BRD4 (0.45) | BRD4KDM4EALDH1A1POLBLMNA | |
| SCHEMBL3175796 | 0.72 | BRD4 (0.53) | BRD4KDM4EALDH1A1POLBLMNA | |
| SCHEMBL3166284 | 0.71 | CASP3 (0.47) | BRD4KDM4EALDH1A1POLBLMNA | |
| SCHEMBL8208981 | 0.68 | BRD4 (0.43) | BRD4KDM4EALDH1A1POLBLMNA | |
| SCHEMBL8208989 | 0.68 | BRD4 (0.42) | BRD4KDM4EALDH1A1POLBLMNA | |
| SCHEMBL3182350 | 0.67 | KDM4E (0.39) | BRD4KDM4EALDH1A1POLBLMNA | |
| SCHEMBL3172374 | 0.67 | CASP3 (0.49) | BRD4KDM4EALDH1A1POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008056898-A1 | CASPASE INHIBITORS BASED ON PYRIDAZINONE SCAFFOLD | LG LIFE SCIENCES LTD. (KR) | 2008-05-15 | — | — | WO | disclosed |