Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8199243 | 0.89 | GRIN2B (0.46) | GRIN2BEPHX1TAAR1SIGMAR1 | |
| SCHEMBL8199188 | 0.87 | GRIN2B (0.40) | GRIN2BTAAR1SIGMAR1 | |
| SCHEMBL8199090 | 0.86 | GRIN2B (0.43) | GRIN2BALDH1A1SIGMAR1 | |
| SCHEMBL8209728 | 0.86 | HRH1 (0.42) | GRIN2BALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8205354 | 0.85 | MEN1 (0.43) | GRIN2BALDH1A1KMT2AMEN1NPC1 | |
| Hydrochloric Acid SCHEMBL8209834 | 0.85 | GRIN2B (0.46) | GRIN2BEPHX1TAAR1SIGMAR1 | |
| SCHEMBL8205279 | 0.84 | GRIN2B (0.48) | GRIN2BALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL8211721 | 0.83 | MCHR1 (0.44) | GRIN2BALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL8205244 | 0.83 | TAAR1 (0.49) | GRIN2BALDH1A1KMT2AMEN1EPHX1 | |
| SCHEMBL8206272 | 0.83 | TAAR1 (0.46) | GRIN2BALDH1A1KMT2AMEN1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0999205-A1 | AMINOCYCLOALKANE COMPOUNDS | Mitsubishi-Tokyo Pharmaceuticals, Inc. (JP) | 2000-05-10 | — | — | EP | disclosed |