Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8214654 | 0.99 | CNR1 (0.44) | CNR1CNR2CHRNA7POLBRORC | |
| SCHEMBL8131789 | 0.78 | POLB (0.47) | POLBNPC1RAB9A | |
| SCHEMBL8212966 | 0.77 | TP53 (0.48) | CNR1CNR2CHRNA7RORC | |
| SCHEMBL8213939 | 0.77 | NPC1 (0.57) | CNR1CNR2CHRNA7RORCNPC1 | |
| SCHEMBL7555526 | 0.77 | CNR1 (0.51) | CNR1CNR2CHRNA7RORC | |
| SCHEMBL8218668 | 0.77 | NPC1 (0.59) | CHRNA7POLBNPC1RAB9A | |
| SCHEMBL8206309 | 0.77 | MAPT (0.50) | CNR1CNR2CHRNA7POLBRORC | |
| SCHEMBL8214395 | 0.77 | SMN1; SMN2 (0.51) | CNR1CNR2CHRNA7RORCNPC1 | |
| Hydrochloric Acid SCHEMBL8205786 | 0.76 | TP53 (0.47) | CNR1CNR2CHRNA7RORC | |
| Hydrochloric Acid SCHEMBL8213598 | 0.76 | NPC1 (0.56) | CNR1CNR2CHRNA7RORCNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000008022-A1 | UREA DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 2000-02-17 | — | — | WO | claimed |
| WO-2000008022-A1 | UREA DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 2000-02-17 | — | — | WO | disclosed |