Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 7/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 8/20 | 0.45 |
| ▸ | PDE4A | P27815 | 6/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.45 |
| ▸ | PPOX | P50336 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7931893 | 0.99 | SCN9A (0.52) | SCN9ATSHRPDE4DPDE4APDE4B | |
| SCHEMBL7922423 | 0.87 | SCN9A (0.48) | SCN9ATSHRPDE4DPDE4APDE4B | |
| SCHEMBL8089641 | 0.84 | RORC (0.40) | SCN9ATSHRRORCLMNASMN1; SMN2 | |
| SCHEMBL8191955 | 0.84 | SCN9A (0.46) | SCN9ATSHRPDE4DPDE4APDE4B | |
| SCHEMBL9260247 | 0.82 | POLB (0.45) | SCN9APDE4DPDE4APDE4BPDE4C | |
| SCHEMBL9262674 | 0.82 | SCN9A (0.41) | SCN9ATSHRLMNASMN1; SMN2 | |
| SCHEMBL8998045 | 0.82 | SCN9A (0.42) | SCN9ATSHRPDE4DPDE4APDE4B | |
| SCHEMBL8763572 | 0.80 | NPSR1 (0.51) | SCN9APDE4DPDE4APDE4BPDE4C | |
| SCHEMBL8083691 | 0.80 | NPC1 (0.44) | SCN9APDE4DPDE4APDE4BPDE4C | |
| SCHEMBL30296512 | 0.80 | SCN9A (0.48) | SCN9APDE4DPDE4BPPOXRORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0493606-B1 | HETEROCYCLE-SUBSTITUTED BENZENE DERIVATIVE, PRODUCTION THEREOF, AND HERBICIDE CONTAINING THE SAME AS ACTIVE INGREDIENT | SAGAMI CHEM RES (JP) | 2000-10-18 | — | — | EP | disclosed |
| EP-1006105-A1 | Benzene derivatives | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2000-06-07 | — | — | EP | disclosed |
| US-5464811-A | Benzene derivatives substituted with heterocyclic ring and herbicides containing same as active ingredients | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1995-11-07 | — | — | US | disclosed |
| US-5424277-A | An N-substituted-3,4,5,6-tetrahydrophthalimide derivative characterized by having a cycloalkoxy group at the 5-position of the phenyl ring on the nitrogen | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1995-06-13 | — | — | US | disclosed |
| US-5391807-A | Methods of preparing fluorobenzene derivatives and related compounds | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1995-02-21 | — | — | US | disclosed |
| US-5344953-A | Fluorobenzene derivatives | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1994-09-06 | — | — | US | disclosed |
| US-5281742-A | Bis(fluorophenyl) carbonate derivatives | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1994-01-25 | — | — | US | disclosed |
| EP-0496347-A2 | Methods of preparing fluorobenzene derivatives and related compounds | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1992-07-29 | — | — | EP | disclosed |
| EP-0493606-A1 | HETEROCYCLE-SUBSTITUTED BENZENE DERIVATIVE, PRODUCTION THEREOF, AND HERBICIDE CONTAINING THE SAME AS ACTIVE INGREDIENT | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1992-07-08 | — | — | EP | disclosed |