Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | PKLR | P30613 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | CCR6 | P51684 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6329625 | 1.00 | PKM (0.64) | PKMNPC1PKLRRAB9AMAPT | |
| SCHEMBL6323332 | 0.92 | GAA (0.67) | PKMNPC1PKLRRAB9AMAPT | |
| SCHEMBL841106 | 0.85 | DHCR7 (0.60) | — | |
| SCHEMBL12730547 | 0.85 | KMT2A (0.64) | PKMSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL4516709 | 0.83 | PKM (0.57) | PKMNPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL3235046 | 0.83 | PKM (0.57) | PKMNPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL3235054 | 0.83 | PKM (0.57) | PKMNPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL8200209 | 0.83 | PKM (0.60) | PKMNPC1PKLRRAB9AMAPT | |
| SCHEMBL6986391 | 0.82 | TSHR (0.64) | PKMRAB9AALDH1A1GAACYP2D6 | |
| SCHEMBL8207825 | 0.82 | ADAM17 (0.67) | PKMNPC1PKLRRAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6121272-A | Bidentate metalloprotease inhibitors | THE PROCTER & GAMBLE COMPANY (US) | 2000-09-19 | — | — | US | disclosed |