Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | ATM | Q13315 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | MGAM | O43451 | 3/20 | 0.64 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.64 |
| ▸ | TP53 | P04637 | 4/20 | 0.61 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | FLT3 | P36888 | 1/20 | 0.55 |
| ▸ | KIF11 | P52732 | 1/20 | 0.55 |
| ▸ | CNR2 | P34972 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8211459 | 0.90 | MGAM (0.77) | KMT2AMEN1ATML3MBTL1MGAM | |
| SCHEMBL7887075 | 0.90 | KMT2A (0.70) | KMT2AMEN1ATML3MBTL1MGAM | |
| SCHEMBL13561194 | 0.86 | KMT2A (0.74) | KMT2AMEN1ATML3MBTL1MGAM | |
| SCHEMBL8213046 | 0.82 | MGAM (0.73) | KMT2AMEN1L3MBTL1MGAMAMY1A | |
| SCHEMBL8248232 | 0.81 | CNR2 (0.65) | KMT2AMEN1ATML3MBTL1TP53 | |
| SCHEMBL8290383 | 0.80 | KMT2A (0.87) | KMT2AMEN1ATML3MBTL1MGAM | |
| SCHEMBL7888385 | 0.80 | MGAM (0.73) | KMT2AMEN1ATML3MBTL1MGAM | |
| SCHEMBL17183511 | 0.80 | KMT2A (0.72) | KMT2AMEN1ATML3MBTL1MGAM | |
| SCHEMBL8288791 | 0.79 | KMT2A (1.00) | KMT2AMEN1ATML3MBTL1MGAM | |
| SCHEMBL8212882 | 0.79 | MGAM (0.64) | KMT2AMEN1MGAMAMY1ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143777-A | ENZYME INHIBITORS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-11-07 | — | — | US | disclosed |