Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.65 |
| ▸ | CNR1 | P21554 | 1/20 | 0.65 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | RORC | P51449 | 2/20 | 0.52 |
| ▸ | FLT3 | P36888 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7886940 | 0.92 | TAAR1 (0.61) | CNR2CNR1TAAR1MAPTKDM4E | |
| SCHEMBL8206909 | 0.91 | RORC (0.63) | CNR2CNR1MAPTKDM4EHSD17B10 | |
| Bicarbonate SCHEMBL7886942 | 0.90 | CNR2 (0.66) | CNR2CNR1TAAR1MAPTKDM4E | |
| SCHEMBL8212606 | 0.82 | CNR2 (0.61) | CNR2CNR1MAPTKDM4EHSD17B10 | |
| SCHEMBL7890904 | 0.82 | RORC (0.67) | CNR2CNR1MAPTKDM4EHSD17B10 | |
| SCHEMBL8206447 | 0.81 | KMT2A (0.66) | CNR2TAAR1MAPTKMT2AMEN1 | |
| SCHEMBL3801324 | 0.81 | RORC (0.68) | CNR2CNR1MAPTKDM4EALDH1A1 | |
| SCHEMBL8248235 | 0.80 | MAPT (0.58) | CNR2CNR1MAPTKDM4EHSD17B10 | |
| SCHEMBL8200351 | 0.80 | CNR2 (0.54) | CNR2CNR1MAPTKDM4EHSD17B10 | |
| SCHEMBL8207571 | 0.80 | CNR2 (0.58) | CNR2CNR1MAPTKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143777-A | ENZYME INHIBITORS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-11-07 | — | — | US | disclosed |