Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 2/20 | 0.64 |
| ▸ | HNF4A | P41235 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | PLAT | P00750 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2935188 | 0.79 | BCAT2 (0.84) | BCAT2HNF4ANPC1RAB9AKDM4E | |
| SCHEMBL29427545 | 0.79 | BCAT2 (1.00) | BCAT2HNF4ANPC1RAB9AKDM4E | |
| SCHEMBL132986 | 0.79 | BCAT2 (1.00) | BCAT2HNF4ANPC1RAB9AKDM4E | |
| SCHEMBL27734030 | 0.79 | BACE1 (0.50) | HNF4AKDM4EALDH1A1MAPTHPGD | |
| Hydrochloric Acid SCHEMBL1785690 | 0.77 | BCAT2 (0.96) | BCAT2HNF4ANPC1RAB9AKDM4E | |
| Urea SCHEMBL28572437 | 0.77 | BCAT2 (0.96) | BCAT2HNF4ANPC1RAB9AKDM4E | |
| Hydrochloric Acid SCHEMBL5180095 | 0.77 | BCAT2 (0.96) | BCAT2HNF4ANPC1RAB9AKDM4E | |
| SCHEMBL28355265 | 0.77 | BCAT2 (0.96) | BCAT2HNF4ANPC1RAB9AKDM4E | |
| Ammonia Solution, Strong SCHEMBL28275782 | 0.77 | BCAT2 (0.96) | BCAT2HNF4ANPC1RAB9AKDM4E | |
| Hydrochloric Acid SCHEMBL27487444 | 0.77 | BCAT2 (0.96) | BCAT2HNF4ANPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999048868-A9 | HETEROCYCLIC CLASSES OF COMPOUNDS FOR THE MODULATING TYROSINE PROTEIN KINASE | SUGEN INC (US) | 2000-04-20 | — | — | WO | disclosed |