Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 2/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1464689 | 0.83 | PIN1 (0.50) | PIN1MMP8ALDH1A1RECQLTSHR | |
| SCHEMBL11313853 | 0.79 | PIN1 (0.46) | PIN1MMP8ALDH1A1RECQLTSHR | |
| SCHEMBL2320350 | 0.79 | POLB (0.49) | PIN1MMP8ALDH1A1RECQLTSHR | |
| SCHEMBL11771628 | 0.78 | MMP8 (0.50) | PIN1MMP8ALDH1A1RECQLTSHR | |
| SCHEMBL10816315 | 0.77 | POLB (0.48) | PIN1MMP8ALDH1A1RECQLTSHR | |
| SCHEMBL5552914 | 0.77 | POLB (0.44) | ALDH1A1CYP1A2PPARAPOLBHPGD | |
| SCHEMBL10708966 | 0.75 | MMP8 (0.53) | PIN1MMP8ALDH1A1RECQLTSHR | |
| SCHEMBL2910521 | 0.74 | PIN1 (0.54) | PIN1MMP8ALDH1A1RECQLTSHR | |
| SCHEMBL7527310 | 0.73 | PIN1 (0.53) | PIN1MMP8ALDH1A1RECQLTSHR | |
| SCHEMBL705709 | 0.73 | PIN1 (0.53) | PIN1MMP8ALDH1A1RECQLTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153705-A | CHAIN-END FUNCTIONALIZED BY ALKYL XANTHATES. | RHODIA CHIMIE (FR) | 2000-11-28 | — | — | US | disclosed |