Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7663551 | 0.72 | ALDH1A1 (0.44) | CA1CA2ALDH1A1HTTLMNA | |
| SCHEMBL8475364 | 0.69 | ALDH1A1 (0.39) | CA1CA2ALDH1A1HTTHPGD | |
| SCHEMBL7756297 | 0.69 | HTT (0.36) | CA1CA2ALDH1A1HTTHPGD | |
| SCHEMBL8067867 | 0.68 | POLB (0.49) | ALDH1A1HTTMEN1LMNAHPGD | |
| SCHEMBL8473440 | 0.68 | ALDH1A1 (0.38) | CA1CA2ALDH1A1HTT | |
| SCHEMBL7753632 | 0.67 | HTT (0.35) | CA1CA2ALDH1A1HTTMEN1 | |
| SCHEMBL8471904 | 0.67 | POLB (0.48) | ALDH1A1HTTMEN1LMNAHPGD | |
| SCHEMBL6427157 | 0.66 | TDP1 (0.54) | CA1CA2ALDH1A1HTTMEN1 | |
| SCHEMBL17208243 | 0.66 | CA1 (0.38) | CA1CA2ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL13826361 | 0.66 | CA1 (0.46) | CA1CA2ALDH1A1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6051571-A | NERVOUS SYSTEM DISORDERS; CARDIOVASCULAR DISORDERS | CENTAUR PHARMACEUTICALS, INC. (US) | 2000-04-18 | — | — | US | disclosed |
| US-6040444-A | Process for preparing furan nitrone compounds | CENTAUR PHARMACEUTICALS, INC. (US) | 2000-03-21 | — | — | US | disclosed |
| US-5942507-A | REAGANTS FOR DETECTION FREE RADICALS | CENTAUR PHARMACEUTICALS, INC. (US) | 1999-08-24 | — | — | US | disclosed |