Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 13/20 | 0.46 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL272970 | 0.99 | KCNH2 (0.47) | KCNH2RIOK2GBA1ALDH1A1KDM4E | |
| SCHEMBL29397420 | 0.99 | KCNH2 (0.47) | KCNH2RIOK2GBA1ALDH1A1KDM4E | |
| SCHEMBL29397508 | 0.99 | KCNH2 (0.47) | KCNH2RIOK2GBA1ALDH1A1KDM4E | |
| SCHEMBL272969 | 0.99 | KCNH2 (0.47) | KCNH2RIOK2GBA1ALDH1A1KDM4E | |
| Bromide SCHEMBL30705401 | 0.98 | KCNH2 (0.48) | KCNH2RIOK2GBA1ALDH1A1KDM4E | |
| SCHEMBL28025013 | 0.88 | KCNH2 (0.44) | KCNH2RIOK2ALDH1A1KDM4EMAPK1 | |
| SCHEMBL4343598 | 0.85 | KCNH2 (0.64) | KCNH2RIOK2ALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL4343601 | 0.85 | KCNH2 (0.64) | KCNH2RIOK2ALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL8654656 | 0.84 | KCNH2 (0.47) | KCNH2RIOK2ALDH1A1KDM4EMAPK1 | |
| SCHEMBL8654659 | 0.84 | KCNH2 (0.47) | KCNH2RIOK2ALDH1A1KDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6107098-A | MIXTURE OF SODIUM CITRATE AND ETHYLENEDIAMINETETRAACETIC ACID AS METAL MASKING AGENTS, ALKALINE BUFFER, SOLUBILIZING AGENT, AND 2-(5-BROMO-S-PYRIDYLAZO)-5-DIETHYLAMINOPHENOL DYE WHICH COMPLEXES WITH URANIUM; RAPID, ACCURATE TEST FOR BATTLEFIELDS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 2000-08-22 | — | — | US | disclosed |