SCHEMBL8654656

SCHEMBL8654656

CCN(CC)c1ccc(/N=N/c2ccc(Cl)cn2)c(O)c1

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 13/20 0.47
KMT2A Q03164 3/20 0.43
RIOK2 Q9BVS4 1/20 0.42
MAPT P10636 5/20 0.39
ALDH1A1 P00352 3/20 0.39
RAB9A P51151 2/20 0.39
GAA P10253 2/20 0.38
MAPK1 P28482 1/20 0.38
KDM4E B2RXH2 2/20 0.38
MEN1 O00255 2/20 0.38
LMNA P02545 1/20 0.38
CRHBP P24387 1/20 0.38
CRHR2 Q13324 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
NPC1 O15118 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8654659 1.00 KCNH2 (0.47) KCNH2KMT2ARIOK2MAPTALDH1A1
SCHEMBL10604052 0.86 KCNH2 (0.64) KCNH2KMT2ARIOK2MAPTALDH1A1
SCHEMBL29397420 0.85 KCNH2 (0.47) KCNH2KMT2ARIOK2MAPTALDH1A1
SCHEMBL29397508 0.85 KCNH2 (0.47) KCNH2KMT2ARIOK2MAPTALDH1A1
SCHEMBL272969 0.85 KCNH2 (0.47) KCNH2KMT2ARIOK2MAPTALDH1A1
SCHEMBL272970 0.85 KCNH2 (0.47) KCNH2KMT2ARIOK2MAPTALDH1A1
SCHEMBL7208315 0.84 KCNH2 (0.45) KCNH2KMT2AMAPTALDH1A1RAB9A
SCHEMBL8206882 0.84 KCNH2 (0.46) KCNH2KMT2ARIOK2MAPTALDH1A1
Bromide SCHEMBL30705401 0.84 KCNH2 (0.48) KCNH2KMT2ARIOK2MAPTALDH1A1
SCHEMBL13662909 0.84 MAPT (0.45) KCNH2KMT2AMAPTALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100420935-C Lead determination solution and colorimetric determination tube therefor LI BAI (CN) 2008-09-24 CN claimed
CN-2884185-Y Colorimetric estimation tube for lead BAI LI (CN) 2007-03-28 CN claimed
CN-1800826-A Lead determination solution and colorimetric determination tube therefor BAI LI (CN) 2006-07-12 CN claimed
CN-100420935-C Lead determination solution and colorimetric determination tube therefor LI BAI (CN) 2008-09-24 CN disclosed
CN-2884185-Y Colorimetric estimation tube for lead BAI LI (CN) 2007-03-28 CN disclosed
CN-1800826-A Lead determination solution and colorimetric determination tube therefor BAI LI (CN) 2006-07-12 CN disclosed
US-5790627-A Method and apparatus for observing a specimen using an X-ray microscope RESEARCH DEVELOPMENT CORP. (JP) 1998-08-04 US disclosed
EP-0763512-A1 AIR BAG GAS GENERATING AGENT OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 1997-03-19 EP disclosed