Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL7425820 | 0.92 | KDM4E (0.53) | LMNAKDM4EALDH2POLBMAPT | |
| SCHEMBL8211919 | 0.90 | KDM4E (0.54) | LMNAKDM4EALDH2POLBMAPT | |
| SCHEMBL7881605 | 0.89 | MAPT (0.52) | LMNAKDM4EMAPTKMT2AMEN1 | |
| SCHEMBL8200327 | 0.88 | KMT2A (0.52) | LMNAKDM4EPOLBMAPTGAA | |
| SCHEMBL8220300 | 0.86 | MAPT (0.48) | LMNAKDM4EALDH2POLBMAPT | |
| SCHEMBL7892994 | 0.84 | USP2 (0.45) | MAPTKMT2AMEN1TP53HPGD | |
| SCHEMBL7887105 | 0.84 | SMN1; SMN2 (0.43) | LMNAKDM4EPOLBKMT2AMEN1 | |
| SCHEMBL8297238 | 0.82 | POLB (0.53) | LMNAKDM4EALDH2POLBMAPT | |
| SCHEMBL8199987 | 0.82 | LMNA (0.57) | LMNAKDM4EALDH2POLBMAPT | |
| SCHEMBL7881446 | 0.81 | NPC1 (0.49) | LMNAKDM4EPOLBKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143777-A | ENZYME INHIBITORS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-11-07 | — | — | US | disclosed |