Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL308105 | 0.85 | CA5A (0.50) | CA5ACA5BMEN1ALDH1A1TSHR | |
| Thiosulfuric Acid SCHEMBL8197744 | 0.84 | CA1 (0.35) | MEN1ALDH1A1TSHRKMT2A | |
| Sulfuric Acid SCHEMBL7062511 | 0.81 | CA5A (0.46) | CA5ACA5BMEN1ALDH1A1TSHR | |
| Sulfuric Acid SCHEMBL1239739 | 0.80 | CA5A (0.67) | CA5ACA5BMEN1ALDH1A1TSHR | |
| Sulfuric Acid SCHEMBL4635604 | 0.80 | CA5A (0.67) | CA5ACA5BMEN1ALDH1A1TSHR | |
| Sulfuric Acid SCHEMBL9400223 | 0.76 | CA5A (0.60) | CA5ACA5BMEN1ALDH1A1TSHR | |
| Sulfuric Acid SCHEMBL9859969 | 0.76 | CA5A (0.60) | CA5ACA5BMEN1ALDH1A1TSHR | |
| Sulfuric Acid SCHEMBL27535582 | 0.76 | CA5A (0.60) | CA5ACA5BMEN1ALDH1A1TSHR | |
| Sulfuric Acid SCHEMBL8907828 | 0.76 | CA5A (0.40) | CA5ACA5BMEN1ALDH1A1TSHR | |
| Thiosulfuric Acid SCHEMBL1812919 | 0.76 | CA5A (0.56) | CA5ACA5BMEN1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6068853-A | CHRONOBIOLOGY IN THAT THE DRUG DELIVERY SYSTEM CAN BE DESIGNED TO MODULATE ACTIVE AGENT DELIVERY IN ACCORDANCE WITH BIOLOGICAL RHYTHMS; OSCILLATION CHEMICAL SYSTEM | NOVARTIS CORPORATION (US) | 2000-05-30 | — | — | US | disclosed |
| EP-0755244-A1 | TEMPORALLY CONTROLLED DRUG DELIVERY SYSTEMS | Novartis AG (CH) | 1997-01-29 | — | — | EP | disclosed |
| WO-1995028144-A1 | TEMPORALLY CONTROLLED DRUG DELIVERY SYSTEMS | CIBA-GEIGY AG (CH) | 1995-10-26 | — | — | WO | disclosed |