Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 8/20 | 0.39 |
| ▸ | DRD3 | P35462 | 8/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | PKLR | P30613 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8207143 | 0.80 | DRD2 (0.42) | DAOFFAR1DRD2DRD3PTGS2 | |
| SCHEMBL15864968 | 0.76 | FFAR1 (0.47) | DAOFFAR1DRD2DRD3MAPT | |
| SCHEMBL17272684 | 0.76 | FFAR1 (0.47) | DAOFFAR1DRD2DRD3MAPT | |
| SCHEMBL15865467 | 0.76 | FFAR1 (0.49) | DAOFFAR1DRD2DRD3PTGS2 | |
| SCHEMBL6738922 | 0.76 | FFAR1 (0.49) | DAOFFAR1DRD2DRD3PTGS2 | |
| SCHEMBL26750469 | 0.76 | FFAR1 (0.49) | DAOFFAR1DRD2DRD3MAPT | |
| SCHEMBL5917859 | 0.76 | FFAR1 (0.49) | DAOFFAR1DRD2DRD3MAPT | |
| SCHEMBL15865348 | 0.76 | FFAR1 (0.49) | DAOFFAR1DRD2DRD3PTGS2 | |
| SCHEMBL15864965 | 0.76 | FFAR1 (0.47) | DAOFFAR1DRD2DRD3MAPT | |
| SCHEMBL1877574 | 0.74 | CA2 (0.48) | DAOFFAR1DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000058301-A1 | N-[2-(4-AMINOPHYL)ETHYL]-2,3-DIHYDRO-1,4-BENZODIOXINE-2-METHANAMINE, PRODUCTION AND THERAPEUTIC USE THEREOF | SANOFI-SYNTHELABO (FR) | 2000-10-05 | — | — | WO | disclosed |