Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.53 |
| ▸ | MAOA | P21397 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.35 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21241253 | 0.82 | CYP19A1 (0.50) | MAOBMAOAALDH1A1HPGDCYP19A1 | |
| SCHEMBL17189423 | 0.74 | CYP3A4 (0.43) | MAOAKDM4EGAA | |
| SCHEMBL9747026 | 0.74 | ALDH1A1 (0.65) | MAOBMAOAALDH1A1HPGDCYP19A1 | |
| SCHEMBL523446 | 0.74 | ALDH1A1 (0.65) | MAOBMAOAALDH1A1HPGDCYP19A1 | |
| SCHEMBL9745473 | 0.74 | ALDH1A1 (0.65) | MAOBMAOAALDH1A1HPGDCYP19A1 | |
| SCHEMBL21241012 | 0.73 | ALDH1A1 (0.56) | MAOBMAOAALDH1A1HPGDCYP19A1 | |
| SCHEMBL1465968 | 0.73 | TDP1 (0.38) | MAOBALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL11701826 | 0.72 | CYP2A6 (0.48) | ALDH1A1KDM4EMAPK1SMN1; SMN2MEN1 | |
| SCHEMBL29019220 | 0.72 | CYP1A2 (0.43) | KDM4EMAPK1SMN1; SMN2MEN1GAA | |
| SCHEMBL5143806 | 0.71 | ALDH1A1 (0.61) | MAOBMAOAALDH1A1HPGDCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0712904-B1 | Phtalocyanines substituted with groups containing phosphorus | CIBA SC HOLDING AG (CH) | 2000-04-26 | — | — | EP | disclosed |
| US-5641879-A | Phthalocyanines substituted by phosphorus-containing groups | CIBA-GEIGY CORPORATION (US) | 1997-06-24 | — | — | US | disclosed |
| EP-0712904-A1 | Phtalocyanines substituted with groups containing phosphorus | CIBA-GEIGY AG (CH) | 1996-05-22 | — | — | EP | disclosed |